Gene Information
|
Gene Name
|
NBPF12 |
|
Gene ID
|
149013
|
|
Gene Full Name
|
NBPF member 12 |
|
Gene Alias
|
COAS1|KIAA1245 |
|
Transcripts
|
ENSG00000268043
|
|
Virus
|
HPV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Primary cilium, Cytosol;Golgi apparatus, Vesicles, Microtubules, Cytokinetic bridge, Mid piece, Principal piece, End piece; 
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
Q5TAG4
|
|
HGNC ID
|
HGNC:24297
|
|
OMIM ID
|
608607 |
|
Summary
|
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, May 2013] |
Target gene [NBPF12] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5014618 |
chr1 |
171 |
57 |
4 |
232 |
View |
Target gene [NBPF12] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE196215
|
RNA-seq |
8 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
TCGA_CESC
|
DNA methylation sequencing;RNA-seq |
288 |
TCGA |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE165883
|
RNA-seq |
20 |
Illumina NextSeq 500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE143026 - NBPF12 peak across samples
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Peak Plot
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|
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HPV Target gene Detail Information
