Gene Information
|
Gene Name
|
NEK1 |
|
Gene ID
|
4750
|
|
Gene Full Name
|
NIMA related kinase 1 |
|
Gene Alias
|
ALS24|NY-REN-55|OFD2|SRPS2|SRPS2A|SRTD6 |
|
Transcripts
|
ENSG00000137601
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;Nucleoplasm, Primary cilium, Centriolar satellite; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
Q96PY6
|
|
HGNC ID
|
HGNC:7744
|
|
OMIM ID
|
604588 |
|
Summary
|
The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
Target gene [NEK1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6011453 |
chr4 |
5 |
21 |
0 |
26 |
View |
| 6022860 |
chr4 |
4 |
0 |
0 |
4 |
View |
| 6022891 |
chr4 |
4 |
0 |
0 |
4 |
View |
| 6022933 |
chr4 |
4 |
0 |
0 |
4 |
View |
Target gene [NEK1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - NEK1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
