HTLV1 Target gene Detail Information

> NEK4 Gene Search Result


Gene Information
Gene Name NEK4
Gene ID 6787
Gene Full Name NIMA related kinase 4
Gene Alias NRK2|STK2|pp12301
Transcripts ENSG00000114904
Virus HTLV1
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P51957
HGNC ID HGNC:11399
OMIM ID 601959
Summary The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]
Target gene [NEK4] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6004627 chr3 108 1 0 109 View
6012408 chr3 13 8 1 22 View
6012412 chr3 13 8 1 22 View
6013732 chr3 10 8 0 18 View
6014001 chr3 13 3 1 17 View

Target gene [NEK4] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - NEK4 peak across samples

Peak Plot