Gene Information
|
Gene Name
|
PCM1 |
|
Gene ID
|
5108
|
|
Gene Full Name
|
pericentriolar material 1 |
|
Gene Alias
|
PTC4|RET/PCM-1 |
|
Transcripts
|
ENSG00000078674
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Microtubules, Primary cilium, Centriolar satellite, Basal body;Cytosol; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Predicted intracellular proteins |
|
Uniport_ID
|
Q15154
|
|
HGNC ID
|
HGNC:8727
|
|
OMIM ID
|
600299 |
|
Summary
|
The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
Target gene [PCM1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6019626 |
chr8 |
3 |
5 |
0 |
8 |
View |
| 6022729 |
chr8 |
5 |
0 |
0 |
5 |
View |
| 6033877 |
chr8 |
3 |
16 |
2 |
21 |
View |
Target gene [PCM1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PCM1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
