HBV Target gene Detail Information

> PDE3B Gene Search Result


Gene Information
Gene Name PDE3B
Gene ID 5140
Gene Full Name phosphodiesterase 3B
Gene Alias HcGIP1|cGIPDE1
Transcripts ENSG00000152270
Virus HBV
Gene Type protein-coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins
Uniport_ID Q13370
HGNC ID HGNC:8779
OMIM ID 602047
Summary Enables 3',5'-cyclic-AMP phosphodiesterase activity. Involved in several processes, including negative regulation of angiogenesis; negative regulation of lipid catabolic process; and regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in membrane. Part of guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [PDE3B] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002895 chr11 180 8 4 192 View
1008736 chr11 5 6 8 19 View
1013248 chr11 3 2 0 5 View
1013266 chr11 3 2 0 5 View
1013317 chr11 3 2 0 5 View
1013341 chr11 3 2 0 5 View
1013408 chr11 3 2 0 5 View
1013971 chr11 3 1 0 4 View
1016818 chr11 1 0 0 1 View
1017093 chr11 1 0 0 1 View

Target gene [PDE3B] related to Omics data
Data ID Experiment type Sample number Platform
GSE252863 scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
S
  GSE247322 		scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - PDE3B expression across samples

Volcano Plot

Bar Plot