HBV Target gene Detail Information

> PPFIA1 Gene Search Result


Gene Information
Gene Name PPFIA1
Gene ID 8500
Gene Full Name PTPRF interacting protein alpha 1
Gene Alias LIP.1|LIP1|LIPRIN
Transcripts ENSG00000131626
Virus HBV
Gene Type protein-coding
HPA Location Info Cytosol;Focal adhesion sites;
Membrane Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q13136
HGNC ID HGNC:9245
OMIM ID 611054
Summary The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Target gene [PPFIA1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003275 chr11 139 10 0 149 View
1003441 chr11 123 10 0 133 View
1010041 chr11 11 2 0 13 View
1021622 chr11 11 2 0 13 View
1021623 chr11 123 10 0 133 View
1021624 chr11 139 10 0 149 View
1041903 chr11 128 15 0 143 View
1041904 chr11 14 3 1 18 View

Target gene [PPFIA1] related to Omics data
Data ID Experiment type Sample number Platform
GSE252863 scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
GSE247322 scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - PPFIA1 peak across samples

Peak Plot

> Dataset: GSE68402 - PPFIA1 peak across samples

Peak Plot

> Dataset: GSE270130 - PPFIA1 peak across samples

Peak Plot

> Dataset: GSE131257 - PPFIA1 peak across samples

Peak Plot