HBV Target gene Detail Information

> PRIM2 Gene Search Result


Gene Information
Gene Name PRIM2
Gene ID 5558
Gene Full Name DNA primase subunit 2
Gene Alias PRIM2A|p58
Transcripts ENSG00000146143
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P49643
HGNC ID HGNC:9370
OMIM ID 176636
Summary This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene, which is also present on chromosome 6. [provided by RefSeq, Apr 2014]
Target gene [PRIM2] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39057060 G1862T
PreC;C
C
Cell line
G
R
S
I
T
 View

Target gene [PRIM2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011619 chr6 6 2 0 8 View
1012412 chr6 3 0 4 7 View
1013114 chr6 2 3 0 5 View
1014244 chr6 4 0 0 4 View
1016326 chr6 0 1 0 1 View
1021925 chr6 6 2 0 8 View
1021926 chr6 2 3 0 5 View
1022167 chr6 0 1 0 1 View
1043167 chr6 3 0 0 3 View

Target gene [PRIM2] related to Omics data
Data ID Experiment type Sample number Platform
GSE252863 scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
GSE247322 scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
 
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - PRIM2 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE94660 - PRIM2 expression across samples

Volcano Plot

Bar Plot