HBV Target gene Detail Information

> PRKDC Gene Search Result


Gene Information
Gene Name PRKDC
Gene ID 5591
Gene Full Name protein kinase, DNA-activated, catalytic subunit
Gene Alias DNA-PKC|DNA-PKcs|DNAPK|DNAPKc|DNPK1|HYRC|HYRC1|IMD26|S473K|XRCC7|p350
Transcripts ENSG00000253729
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P78527
HGNC ID HGNC:9413
OMIM ID 600899
Summary This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
Target gene [PRKDC] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003669 chr8 68 36 14 118 View
1007513 chr8 26 0 0 26 View
1014732 chr8 3 0 0 3 View
1015594 chr8 2 0 0 2 View
1023830 chr8 26 0 0 26 View
1043343 chr8 29 1 0 30 View

Target gene [PRKDC] related to Omics data
Data ID Experiment type Sample number Platform
GSE252863 scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
GSE247322 scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE94660 - PRKDC expression across samples

Volcano Plot

Bar Plot