Gene Information
|
Gene Name
|
PTPRD |
|
Gene ID
|
5789
|
|
Gene Full Name
|
protein tyrosine phosphatase receptor type D |
|
Gene Alias
|
HPTP|HPTPD|HPTPDELTA|PTPD|R-PTP-delta|RPTPDELTA |
|
Transcripts
|
ENSG00000153707
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles;Nucleoplasm;Intracellular and membrane; 
|
|
Membrane Info
|
Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
P23468
|
|
HGNC ID
|
HGNC:9668
|
|
OMIM ID
|
601598 |
|
Summary
|
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010] |
Target gene [PTPRD] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6002187 |
chr9 |
7 |
245 |
20 |
272 |
View |
| 6008490 |
chr9 |
17 |
4 |
24 |
45 |
View |
| 6016496 |
chr9 |
10 |
0 |
2 |
12 |
View |
| 6017085 |
chr9 |
4 |
6 |
1 |
11 |
View |
| 6017453 |
chr9 |
2 |
5 |
3 |
10 |
View |
| 6020237 |
chr9 |
5 |
2 |
0 |
7 |
View |
| 6021284 |
chr9 |
0 |
6 |
0 |
6 |
View |
| 6026855 |
chr9 |
0 |
2 |
0 |
2 |
View |
| 6026856 |
chr9 |
0 |
1 |
1 |
2 |
View |
| 6027343 |
chr9 |
2 |
0 |
0 |
2 |
View |
| 6027353 |
chr9 |
0 |
1 |
1 |
2 |
View |
| 6027354 |
chr9 |
0 |
1 |
1 |
2 |
View |
| 6027652 |
chr9 |
0 |
0 |
2 |
2 |
View |
| 6027813 |
chr9 |
0 |
1 |
0 |
1 |
View |
| 6028440 |
chr9 |
0 |
1 |
0 |
1 |
View |
| 6028841 |
chr9 |
1 |
0 |
0 |
1 |
View |
| 6030883 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 6031149 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 6031220 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 6033524 |
chr9 |
0 |
0 |
0 |
0 |
View |
Target gene [PTPRD] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PTPRD peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
