Gene Information
|
Gene Name
|
PTPRJ |
|
Gene ID
|
5795
|
|
Gene Full Name
|
protein tyrosine phosphatase receptor type J |
|
Gene Alias
|
CD148|DEP1|HPTP eta|HPTPeta|R-PTP-ETA|R-PTP-J|SCC1|THC10 |
|
Transcripts
|
ENSG00000149177
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Cell Junctions;Nucleoli, Nuclear bodies;Secreted to blood; 
|
|
Membrane Info
|
CD markers, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins |
|
Uniport_ID
|
Q12913
|
|
HGNC ID
|
HGNC:9673
|
|
OMIM ID
|
600925 |
|
Summary
|
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Target gene [PTPRJ] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1012900 |
chr11 |
5 |
1 |
0 |
6 |
View |
| 1015863 |
chr11 |
1 |
1 |
0 |
2 |
View |
| 1017166 |
chr11 |
1 |
0 |
0 |
1 |
View |
| 1020346 |
chr11 |
48 |
49 |
20 |
117 |
View |
Target gene [PTPRJ] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE252863
|
scRNA-seq |
10 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE35465
|
Chip-seq;RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
S GSE247322
|
scRNA-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
C GSE270130
|
Chip-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE100400 - PTPRJ expression across samples
|
Volcano Plot
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Bar Plot
|
|
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HBV Target gene Detail Information
