HTLV1 Target gene Detail Information

> S100A8 Gene Search Result

Gene Information

Gene Name	S100A8
Gene ID	6279
Gene Full Name	S100 calcium binding protein A8
Gene Alias	60B8AG\|CAGA\|CFAG\|CGLA\|CP-10\|L1Ag\|MA387\|MIF\|MRP8\|NIF\|P8\|S100-A8
Transcripts	ENSG00000143546
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Intermediate filaments;Cytosol;Secreted to blood;
Membrane Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P05109
HGNC ID	HGNC:10498
OMIM ID	123885
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

Target gene [S100A8] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007644	chr1	42	11	0	53	View
6018053	chr1	9	0	0	9	View

Target gene [S100A8] related to Omics data

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
E GSE19080	Expression array	38	Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE19080 - S100A8 expression across samples
Volcano Plot
Bar Plot