HTLV1 Target gene Detail Information

> SEMA7A Gene Search Result


Gene Information
Gene Name SEMA7A
Gene ID 8482
Gene Full Name semaphorin 7A (JohnMiltonHagen blood group)
Gene Alias CD108|CDw108|H-SEMA-K1|H-Sema-L|JMH|PFIC11|SEMAK1|SEMAL
Transcripts ENSG00000138623
Virus HTLV1
Gene Type protein-coding
HPA Location Info Vesicles;
Membrane Info Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins
Uniport_ID O75326
HGNC ID HGNC:10741
OMIM ID 607961
Summary This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Target gene [SEMA7A] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6012294 chr15 21 2 0 23 View

Target gene [SEMA7A] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
E
  GSE19080 		Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE19080 - SEMA7A expression across samples

Volcano Plot

Bar Plot