Gene Name	SH3BP5
Gene ID	9467
Gene Full Name	SH3 domain binding protein 5
Gene Alias	SAB|SH3BP-5
Transcripts	ENSG00000131370
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoplasm, Nuclear bodies;
Membrane Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O60239
HGNC ID	HGNC:10827
OMIM ID	605612
Summary	Enables guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Acts upstream of or within intracellular signal transduction. Located in cytoplasmic vesicle membrane and nuclear body. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003912	chr3	62	49	25	136	View
6003917	chr3	62	49	25	136	View
6003918	chr3	62	49	25	136	View
6003925	chr3	62	49	25	136	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080	Expression array	38	Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - SH3BP5 peak across samples

Peak Plot