HPV Target gene Detail Information

> SRGAP2B Gene Search Result


Gene Information
Gene Name SRGAP2B
Gene ID 647135
Gene Full Name SLIT-ROBO Rho GTPase activating protein 2B
Gene Alias SRGAP2L|SRGAP2P2
Transcripts ENSG00000196369
Virus HPV
Gene Type protein-coding
HPA Location Info Centrosome, Basal body, Cytosol;
Membrane Info Predicted intracellular proteins
Uniport_ID P0DMP2
HGNC ID HGNC:35237
OMIM ID 614703
Summary This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from incomplete segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2 locus. The encoded protein lacks the GTPase activating protein domain compared to proteins encoded by SLIT-ROBO Rho GTPase activating protein 2. The functionality of the protein encoded by this locus has been questioned, as several normal individuals with homozygous deletions for this locus have been identified, and the expression of this locus appears to be much lower than the similar SLIT-ROBO Rho GTPase activating protein 2C (SRGAP2C) locus. The SRGAP2C locus has been shown to encode a protein that functions antagonistically to SLIT-ROBO Rho GTPase activating protein 2 in cortical neuron development. [provided by RefSeq, Dec 2012]
Target gene [SRGAP2B] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5014614 chr1 1 1 2 4 View
5014615 chr1 4 0 0 4 View
5016952 chr1 47 62 10 119 View

Target gene [SRGAP2B] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE139324 scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE164690 scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE183048 - SRGAP2B peak across samples

Peak Plot

> Dataset: GSE143026 - SRGAP2B peak across samples

Peak Plot