HTLV1 Target gene Detail Information

> STK3 Gene Search Result


Gene Information
Gene Name STK3
Gene ID 6788
Gene Full Name serine/threonine kinase 3
Gene Alias KRS1|MST2
Transcripts ENSG00000104375
Virus HTLV1
Gene Type protein-coding
HPA Location Info Intermediate filaments, Rods & Rings;
Membrane Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q13188
HGNC ID HGNC:11406
OMIM ID 605030
Summary This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Target gene [STK3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6006343 chr8 59 9 2 70 View
6011047 chr8 10 16 2 28 View
6016555 chr8 10 1 1 12 View
6025052 chr8 3 0 0 3 View

Target gene [STK3] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - STK3 peak across samples

Peak Plot