HTLV1 Target gene Detail Information

> TNRC6B Gene Search Result


Gene Information
Gene Name TNRC6B
Gene ID 23112
Gene Full Name trinucleotide repeat containing adaptor 6B
Gene Alias GDSBA
Transcripts ENSG00000100354
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Disease related genes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID Q9UPQ9
HGNC ID HGNC:29190
OMIM ID 610740
Summary Enables RNA binding activity. Involved in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; and regulatory ncRNA-mediated gene silencing. Acts upstream of with a positive effect on miRNA-mediated gene silencing by inhibition of translation. Predicted to be located in cytosol. Predicted to be active in P-body and nucleoplasm. Implicated in subserous uterine fibroid and uterine fibroid. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [TNRC6B] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6008514 chr22 41 3 0 44 View
6010831 chr22 27 1 1 29 View
6011992 chr22 23 1 0 24 View
6024460 chr22 3 0 0 3 View
6028727 chr22 0 1 0 1 View
6030001 chr22 1 0 0 1 View

Target gene [TNRC6B] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
E
  GSE19080 		Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE19080 - TNRC6B expression across samples

Volcano Plot

Bar Plot