Gene Information
|
Gene Name
|
TRIM21 |
|
Gene ID
|
6737
|
|
Gene Full Name
|
tripartite motif containing 21 |
|
Gene Alias
|
RNF81|RO52|Ro/SSA|SSA|SSA1 |
|
Transcripts
|
ENSG00000132109
|
|
Virus
|
IV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm; 
|
|
Membrane Info
|
Enzymes, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
P19474
|
|
HGNC ID
|
HGNC:11312
|
|
OMIM ID
|
109092 |
|
Summary
|
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] |
Target gene [TRIM21] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [TRIM21] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE243629
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE225706
|
Chip-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E GSE135069
|
RNA-seq |
10 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE113702
|
Chip-seq |
52 |
Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE225704
|
ATAC-seq |
3 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E C GSE156060
|
Chip-seq;RNA-seq |
28 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE135069 - TRIM21 expression across samples
|
Volcano Plot
|
Bar Plot
|
> Dataset: GSE156060 - TRIM21 expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
IV Target gene Detail Information
