IV Target gene Detail Information

> TRIM25 Gene Search Result


Gene Information
Gene Name TRIM25
Gene ID 7706
Gene Full Name tripartite motif containing 25
Gene Alias EFP|RNF147|Z147|ZNF147
Transcripts ENSG00000121060
Virus IV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cytosol;Nuclear bodies;
Membrane Info Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q14258
HGNC ID HGNC:12932
OMIM ID 600453
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein is an RNA binding protein, functions as a ubiquitin E3 ligase and is involved in multiple cellular processes, including regulation of antiviral innate immunity. [provided by RefSeq, Sep 2021]
Target gene [TRIM25] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 19454348 E96A
NS1
NS
Cell line
T
View
2 19454348 E97A
NS1
NS
Cell line
T
View
3 19454348 K41A
NS1
NS
Cell line
T
View
4 19454348 R38A
NS1
NS
Cell line
T
View

Target gene [TRIM25] related to Omics data
Data ID Experiment type Sample number Platform
S
  GSE243629
scRNA-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE225706
Chip-seq 6 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE135069
RNA-seq 10 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE113702
Chip-seq 52 Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens)
GSE162632 scRNA-seq 292 Illumina NovaSeq 6000 (Homo sapiens)
GSE191176 scRNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE225704
ATAC-seq 3 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE156060
Chip-seq;RNA-seq 28 Illumina NovaSeq 6000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE135069 - TRIM25 expression across samples

Volcano Plot


Bar Plot


> Dataset: GSE156060 - TRIM25 expression across samples

Volcano Plot


Bar Plot