Gene Information
|
Gene Name
|
XPO1 |
|
Gene ID
|
7514
|
|
Gene Full Name
|
exportin 1 |
|
Gene Alias
|
CRM-1|CRM1|emb|exp1 |
|
Transcripts
|
ENSG00000082898
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nuclear membrane;Vesicles, Cytosol; 
|
|
Membrane Info
|
Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
O14980
|
|
HGNC ID
|
HGNC:12825
|
|
OMIM ID
|
602559 |
|
Summary
|
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015] |
Target gene [XPO1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6012353 |
chr2 |
22 |
1 |
0 |
23 |
View |
| 6018349 |
chr2 |
2 |
7 |
0 |
9 |
View |
| 6020698 |
chr2 |
1 |
0 |
5 |
6 |
View |
Target gene [XPO1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - XPO1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
