Overview of Virus Mutation

The Virus Mutation feature provides the curated mutation information, including virus mutation count, mutation site, mutation type, virus gene/protein/region, virus associated disease, the evidence sentence in the citation, etc. It also provides statistics information of the viral sequence for geographical location.
The table below shows VM count, VM-related diseases, and literature count in 28 types of viruses which are curated by ViMIC 2.0.

Virus Name	VM Count	Hot Disease	Literatire Count
Hepatitis B Virus (HBV)	17901	Hepatitis B, Chronic Liver Cirrhosis Carcinoma, Hepatocellular	1331
Human Papillomavirus (HPV)	4745	Uterine Cervical Neoplasms Cervical Intraepithelial Neoplasia Squamous Intraepithelial Lesions Uterine Cervicitis	280
Epstein-Barr Virus (EBV)	1852	Burkitt Lymphoma Stomach Neoplasms Lymphoma, Extranodal NK-T-Cell Nasopharyngeal Carcinoma Lymphoma, Large B-Cell, Diffuse Infectious Mononucleosis Multiple Sclerosis Lymphoma, B-Cell	124
Merkel Cell Polyomavirus (MCV)	55	Carcinoma, merkel cell	14
Human Immunodeficiency Virus (HIV)	11782	Acquired Immunodeficiency Syndrome	809
Human T-lymphotropic Virus 1 (HTLV1)	410	Paraparesis, Tropical Spastic Leukemia-Lymphoma, Adult T-Cell	50
Influenza Virus (IV)	4596	Influenza A Influenza B	800
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)	13482	COVID-19	1493
Herpes Simplex Virus 1 (HSV1)	376	Encephalitis, herpes simplex Stomatitis, Herpetic Keratitis, Herpetic	108
Herpes Simplex Virus 2 (HSV2)	243	Herpes genitalis	15
Human Cytomegalovirus (HCMV)	1300	HCMV Antigenaemia HCMV DNAemia Pneumonia Enterocolitis Cytomegalovirus Retinitis Esophagitis Hepatitis Gastritis Colitis	234
Varicella-Zoster Virus (VZV)	307	Herpes zoster Chickenpox	41
Hepatitis A Virus (HAV)	167	Hepatitis A Infection	10
Hepatitis C Virus (HCV)	2887	Hepatitis C, Chronic Liver Cirrhosis Carcinoma, Hepatocellular	353
Hepatitis D Virus (HDV)	40	Fulminant HDV hepatitis HDV Infection Chronic HDV HDV-HBV Coinfection	15
Hepatitis E Virus (HEV)	236	Acute Viral Hepatitis Liver Failure, Acute Chronic Hepatitis E	40
Dengue Virus (DENV)	545	Dengue	78
Yellow Fever Virus (YFV)	133	Yellow Fever	23
Japanese Encephalitis Virus (JEV)	316	Encephalitis, Japanese	54
Tick-Borne Encephalitis Virus (TBEV)	219	Encephalitis, tick-borne	21
Crimean-Congo Hemorrhagic Fever Virus (CCHFV)	60	Hemorrhagic Fever, Crimean	6
Chikungunya Virus (CHIKV)	1116	Chikungunya Fever	154
Zika Virus (ZIKV)	471	Guillain-Barre Syndrome Microcephaly	86
Ebola Virus (EBOV)	547	Hemorrhagic fever, ebola	80
Marburg Virus (MARV)	20	Marburg Virus Infection	6
Rabies Virus (RABV)	316	Rabies Virus infection	63
Kaposi's Sarcoma-Associated Herpesvirus (KSHV)	44		20
Xenotropic Murine Leukemia Virus-Related Virus (XMRV)	2	Prostatic Neoplasms	1

Contents Description and
Data Download

Click the virus name to show a virus summary and the information of mutations, and target genes in each virus. VIS-Cistrome factor overlapped records are only provided by viruses that can integrate into the host genome.
Click the VM count number (green button) in the virus of interest to show mutation entries and viral sequence information.
Click the disease name to display the summary of this virus associated disease and literature.