All Curated Mutation Sites in TBEV 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in TBEV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
*Please select one option you are interested in, the page will be automatically redirected.
     
     

Click the button below to quickly view the viral genes/regions/protein for mutation

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E
  
NS1
  
NS3
  
NS4B
  
NS5
  
C
  

ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 20391780 111del
C
capsid
Tick Bites
G
R
S
L
View
2 20391780 F709L
E
envelope
Tick Bites
G
R
S
L
View
3 20391780 V743A
E
envelope
Tick Bites
G
R
S
L
View
4 20391780 S917G
NS1
NS1
Tick Bites
G
R
S
L
View
5 20391780 S1534F
NS3
NS3
Tick Bites
G
R
S
L
View
6 33571754 C351T
E
envelope
Encephalitis, tick-borne
G
R
L
View
7 12477807 T277V
NS1
NS1
Encephalitis, tick-borne
G
R
I
L
View
8 12477807 E279G
NS1
NS1
Encephalitis, tick-borne
G
R
I
L
View
9 15484275 10461_10810del
3'UTR
Encephalitis, tick-borne
G
R
C
L
View
10 24740396 Q32R
C
capsid
Encephalitis, tick-borne
G
R
L
View
11 24740396 K69R
C
capsid
Encephalitis, tick-borne
G
R
L
View
12 24740396 D100N
C
capsid
Encephalitis, tick-borne
G
R
L
View
13 24740396 111del
C
capsid
Encephalitis, tick-borne
G
R
L
View
14 24740396 S141G
NS1
NS1
Encephalitis, tick-borne
G
R
L
View
15 24740396 F108V
NS2B
NS2B
Encephalitis, tick-borne
G
R
L
View
16 24740396 R16K
NS3
NS3
Encephalitis, tick-borne
G
R
L
View
17 24740396 S45F
NS3
NS3
Encephalitis, tick-borne
G
R
L
View
18 24740396 M95V
NS4B
NS4B
Encephalitis, tick-borne
G
R
L
View
19 24740396 V179A
NS4B
NS4B
Encephalitis, tick-borne
G
R
L
View
20 24740396 A213V
NS4B
NS4B
Encephalitis, tick-borne
G
R
L
View
21 24740396 S634T
NS5
NS5
Encephalitis, tick-borne
G
R
L
View
22 24740396 R677K
NS5
NS5
Encephalitis, tick-borne
G
R
L
View
23 24740396 I692V
NS5
NS5
Encephalitis, tick-borne
G
R
L
View
24 24740396 A724S
NS5
NS5
Encephalitis, tick-borne
G
R
L
View
25 24740396 A151V
prM
prM
Encephalitis, tick-borne
G
R
L
View
26 36362200 T76A
E
envelope
Encephalitis, tick-borne
R
View
27 36362200 K457R
E
envelope
Encephalitis, tick-borne
R
View
28 36362200 I364M
E
envelope
Encephalitis, tick-borne
R
View
29 36362200 H130Y
E
envelope
Encephalitis, tick-borne
R
View
30 36362200 T335S
E
envelope
Encephalitis, tick-borne
R
View
31 36362200 M176L
E
envelope
Encephalitis, tick-borne
R
View
32 36362200 V161M
NS1
NS1
Encephalitis, tick-borne
R
View
33 36362200 S262A
NS1
NS1
Encephalitis, tick-borne
R
View
34 36362200 I274L
NS1
NS1
Encephalitis, tick-borne
R
View
35 36362200 R148K
NS1
NS1
Encephalitis, tick-borne
R
View
36 36362200 R52T
NS2A
NS2A
Encephalitis, tick-borne
R
View
37 36362200 L155Y
NS2A
NS2A
Encephalitis, tick-borne
R
View
38 36362200 V33A
NS2B
NS2B
Encephalitis, tick-borne
R
View
39 36362200 E63D
NS2B
NS2B
Encephalitis, tick-borne
R
View
40 36362200 K314R
NS3
NS3
Encephalitis, tick-borne
R
View
41 36362200 D404E
NS3
NS3
Encephalitis, tick-borne
R
View
42 36362200 R584K
NS3
NS3
Encephalitis, tick-borne
R
View
43 36362200 M56V
NS4A
NS4A
Encephalitis, tick-borne
R
View
44 36362200 I54M
NS4B
NS4B
Encephalitis, tick-borne
R
View
45 36362200 L208V
NS4B
NS4B
Encephalitis, tick-borne
R
View
46 36362200 T226S
NS5
NS5
Encephalitis, tick-borne
R
View
47 36362200 E290D
NS5
NS5
Encephalitis, tick-borne
R
View
48 36362200 H696P
NS5
NS5
Encephalitis, tick-borne
R
View
49 36362200 K872R
NS5
NS5
Encephalitis, tick-borne
R
View
50 36362200 D890E
NS5
NS5
Encephalitis, tick-borne
R
View
51 36362200 K20R
NS5
NS5
Encephalitis, tick-borne
R
View
52 36362200 I31V
NS5
NS5
Encephalitis, tick-borne
R
View
53 36362200 R44K
NS5
NS5
Encephalitis, tick-borne
R
View
54 36362200 K113R
NS5
NS5
Encephalitis, tick-borne
R
View
55 36362200 K162R
NS5
NS5
Encephalitis, tick-borne
R
View
56 36362200 V260T
NS5
NS5
Encephalitis, tick-borne
R
View
57 36362200 K404R
NS5
NS5
Encephalitis, tick-borne
R
View
58 36362200 I590V
NS5
NS5
Encephalitis, tick-borne
R
View
59 36362200 K854R
NS5
NS5
Encephalitis, tick-borne
R
View
60 28814513 S603T
NS5
NS5
Encephalitis, tick-borne
Cell line
G
R
View
61 19802385 E170G
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
62 19802385 D203G
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
63 19802385 D67G
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
64 19802385 D67N
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
65 19802385 E84K
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
66 19802385 E155G
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
67 19802385 E84G
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
68 19802385 S47A
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
69 19802385 S88G
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
70 19802385 D178E
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
71 19802385 D277E
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
72 19802385 T115A
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
73 19802385 S267A
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
74 19802385 T427A
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
75 19802385 T431S
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
76 19802385 V433I
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
77 19802385 L437V
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
View
78 19802385 E122G
E
envelope
Meningoencephalitis
Encephalitis
Cell line
G
R
S
L
View
79 19802385 D277A
E
envelope
Meningoencephalitis
Encephalitis
Cell line
R
View
80 31142664 E460D
NS5
NS5
Cell line
D
G
R
L
View
81 31142664 Y453H
NS5
NS5
Cell line
D
G
R
L
View
82 15039543 G10473A
3'UTR
Cell line
G
R
View
83 15039543 A10922G
3'UTR
Cell line
G
R
View
84 15039543 S40P
E
envelope
Cell line
G
R
View
85 24808743 E122G
E
envelope
Cell line
G
R
View
86 24808743 A1342G
E
envelope
Cell line
G
R
View
87 24808743 G101G
E
envelope
Cell line
G
R
View
88 24808743 T1277G
E
envelope
Cell line
G
R
View
89 24808743 G148G
E
envelope
Cell line
G
R
View
90 24808743 G1415T
E
envelope
Cell line
G
R
View
91 24808743 G191G
E
envelope
Cell line
G
R
View
92 24808743 T1544C
E
envelope
Cell line
G
R
View
93 24808743 L224L
E
envelope
Cell line
G
R
View
94 24808743 C1644T
E
envelope
Cell line
G
R
View
95 24808743 S425S
NS1
NS1
Cell line
G
R
View
96 24808743 T2246C
NS1
NS1
Cell line
G
R
View
97 24808743 E36V
NS1
NS1
Cell line
G
R
View
98 24808743 A2569T
NS1
NS1
Cell line
G
R
View
99 24808743 P130P
NS1
NS1
Cell line
G
R
View
100 24808743 A2894G
NS1
NS1
Cell line
G
R
View
101 24808743 S338F
NS3
NS3
Cell line
G
R
View
102 24808743 C5614T
NS3
NS3
Cell line
G
R
View
103 24808743 D344Y
NS3
NS3
Cell line
G
R
View
104 24808743 G5652T
NS3
NS3
Cell line
G
R
View
105 15039543 V378A
NS5
NS5
Cell line
G
R
View
106 15039543 R674K
NS5
NS5
Cell line
G
R
View
107 15039543 T794A
NS5
NS5
Cell line
G
R
View
108 15039543 T1089C
ORF
Cell line
G
R
View
109 15039543 C1286T
ORF
Cell line
G
R
View
110 15039543 A1847T
ORF
Cell line
G
R
View
111 15039543 G7199A
ORF
Cell line
G
R
View
112 15039543 T8797C
ORF
Cell line
G
R
View
113 15039543 G9685A
ORF
Cell line
G
R
View
114 15039543 A10044G
ORF
Cell line
G
R
View
115 24808743 V149A
prM
prM
Cell line
G
R
View
116 24808743 T149C
prM
prM
Cell line
G
R
View
117 18562534 I6V
C
capsid
Cell line
G
R
View
118 18562534 A148G
C
capsid
Cell line
G
R
View
119 11000232 309delK
E
envelope
Cell line
G
R
View
120 11000232 F332Y
E
envelope
Cell line
G
R
View
121 11000232 K309L
E
envelope
Cell line
G
R
View
122 11000232 D308E
E
envelope
Cell line
G
R
View
123 11000232 K311E
E
envelope
Cell line
G
R
View
124 11000232 D308K
E
envelope
Cell line
G
R
View
125 11000232 T310K
E
envelope
Cell line
G
R
View
126 11000232 10378_10847del
3'UTR
Cell line
G
R
View
127 11000232 10378_10919del
3'UTR
Cell line
G
R
View
128 18562534 E122K
E
envelope
Cell line
G
R
View
129 18562534 G1333A
E
envelope
Cell line
G
R
View
130 18562534 G1557A
E
envelope
Cell line
G
R
View
131 18562534 88delR
prM
prM
Cell line
G
R
View
132 18562534 S85F
prM;M
prM
Cell line
G
R
View
133 18562534 R89H
prM;M
prM
Cell line
G
R
View
134 18562534 C734T
prM;M
prM
Cell line
G
R
View
135 18562534 C888T
prM;M
prM
Cell line
G
R
View
136 18562534 G743A
prM;M
prM
Cell line
G
R
View
137 11413378 C10884T
3'UTR
Cell line
R
View
138 11413378 T10884C
3'UTR
Cell line
R
View
139 32824843 T282C
3'UTR
Cell line
R
S
View
140 32824843 G52A
5'UTR
Cell line
R
S
View
141 11413378 I45F
C
capsid
Cell line
R
View
142 11413378 H496R
E
envelope
Cell line
R
View
143 32988388 A83T
E
envelope
Cell line
R
I
T
View
144 32988388 A463S
E
envelope
Cell line
R
I
T
View
145 39973341 E402G
E
envelope
Cell line
D
View
146 11356970 A1337G
E
envelope
Cell line
R
View
147 11356970 A1232G
E
envelope
Cell line
R
View
148 11356970 G1339A
E
envelope
Cell line
R
View
149 11356970 C1340A
E
envelope
Cell line
R
View
150 11356970 C1576T
E
envelope
Cell line
R
View
151 11356970 C1901A
E
envelope
Cell line
R
View
152 11356970 T1446A
E
envelope
Cell line
R
View
153 11356970 G1447A
E
envelope
Cell line
R
View
154 11356970 G1222A
E
envelope
Cell line
R
View
155 11356970 C1669A
E
envelope
Cell line
R
View
156 11356970 G2131A
E
envelope
Cell line
R
View
157 11356970 G1123A
E
envelope
Cell line
R
View
158 11356970 G1855A
E
envelope
Cell line
R
View
159 11356970 G1338A
E
envelope
Cell line
R
View
160 11356970 G1573A
E
envelope
Cell line
R
View
161 11356970 T2247C
E
envelope
Cell line
R
View
162 11356970 A1580G
E
envelope
Cell line
R
View
163 11356970 G1729A
E
envelope
Cell line
R
View
164 11356970 E122G
E
envelope
Cell line
R
View
165 11356970 Q87R
E
envelope
Cell line
R
View
166 11356970 A123K
E
envelope
Cell line
R
View
167 11356970 L202F
E
envelope
Cell line
R
View
168 11356970 T310K
E
envelope
Cell line
R
View
169 11356970 S158R
E
envelope
Cell line
R
View
170 11356970 G159R
E
envelope
Cell line
R
View
171 11356970 E84K
E
envelope
Cell line
R
View
172 11356970 Q233K
E
envelope
Cell line
R
View
173 11356970 E387K
E
envelope
Cell line
R
View
174 11356970 E51K
E
envelope
Cell line
R
View
175 11356970 E295K
E
envelope
Cell line
R
View
176 11356970 E201K
E
envelope
Cell line
R
View
177 11356970 D203G
E
envelope
Cell line
R
View
178 11356970 D253N
E
envelope
Cell line
R
View
179 37715951 E230K
E
envelope
Cell line
R
S
L
View
180 37715951 G278R
E
envelope
Cell line
R
S
L
View
181 37715951 K311N
E
envelope
Cell line
R
S
L
View
182 37715951 E365A
E
envelope
Cell line
R
S
L
View
183 11413378 R496H
E
envelope
Cell line
R
View
184 2398538 Y384H
E
envelope
Cell line
R
I
View
185 11413378 T2688A
NS5
NS5
Cell line
R
View
186 11413378 M3385I
NS5
NS5
Cell line
R
View
187 39973341 L3122F
NS5
NS5
Cell line
D
View
188 39973341 Y3278F
NS5
NS5
Cell line
D
View
189 14557621 88delR
prM
prM
Cell line
View
190 32824843 A315G
C
capsid
Cell line
R
S
View
191 32824843 A913G
E
envelope
Cell line
R
S
View
192 32824843 C1078T
E
envelope
Cell line
R
S
View
193 32824843 A1411T
E
envelope
Cell line
R
S
View
194 32824843 T305A
E
envelope
Cell line
R
S
View
195 32824843 P360S
E
envelope
Cell line
R
S
View
196 32824843 M471L
E
envelope
Cell line
R
S
View
197 32824843 G169A
NS1
NS1
Cell line
R
S
View
198 32824843 G237A
NS1
NS1
Cell line
R
S
View
199 32824843 V57I
NS1
NS1
Cell line
R
S
View
200 32824843 T605C
NS2A
NS2A
Cell line
R
S
View
201 32824843 V202A
NS2A
NS2A
Cell line
R
S
View
202 32824843 G97A
NS2B
NS2B
Cell line
R
S
View
203 32824843 V33M
NS2B
NS2B
Cell line
R
S
View
204 32824843 T978C
NS3
NS3
Cell line
R
S
View
205 32824843 A1314G
NS3
NS3
Cell line
R
S
View
206 32824843 C240T
NS4B
NS4B
Cell line
R
S
View
207 32824843 G253T
NS4B
NS4B
Cell line
R
S
View
208 32824843 T262A
NS4B
NS4B
Cell line
R
S
View
209 32824843 A85S
NS4B
NS4B
Cell line
R
S
View
210 32824843 F88I
NS4B
NS4B
Cell line
R
S
View
211 32824843 G333A
NS5
NS5
Cell line
R
S
View
212 32824843 A529C
NS5
NS5
Cell line
R
S
View
213 32824843 C2332T
NS5
NS5
Cell line
R
S
View
214 32824843 A2588G
NS5
NS5
Cell line
R
S
View
215 32824843 T177P
NS5
NS5
Cell line
R
S
View
216 32824843 L778F
NS5
NS5
Cell line
R
S
View
217 32824843 N863S
NS5
NS5
Cell line
R
S
View
218 32824843 C101T
prM
prM
Cell line
R
S
View
219 32824843 T34I
prM
prM
Cell line
R
S
View
Contents
Description

The table shows all curated mutation sites of TBEV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.