All Curated Mutation Sites in HSV2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HSV2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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Click the button below to quickly view the viral genes/regions/protein for mutation

Show All
  
TK
  
DNA pol
  
UL52
  
UL5
  
UL30
  
UL23
  

ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 26338148 M910T
DNA pol
UL30
HSV-2 Infection
D
R
View
2 26338148 R628C
DNA pol
UL30
HSV-2 Infection
R
View
3 26338148 A9T
DNA pol
UL30
HSV-2 Infection
R
View
4 26338148 P15S
DNA pol
UL30
HSV-2 Infection
R
View
5 26338148 R41H
DNA pol
UL30
HSV-2 Infection
R
View
6 26338148 L60P
DNA pol
UL30
HSV-2 Infection
R
View
7 26338148 E139K
DNA pol
UL30
HSV-2 Infection
R
View
8 26338148 T202M
DNA pol
UL30
HSV-2 Infection
R
View
9 26338148 A300T
DNA pol
UL30
HSV-2 Infection
R
View
10 26338148 E678G
DNA pol
UL30
HSV-2 Infection
R
View
11 26338148 A547V
DNA pol
UL30
HSV-2 Infection
R
View
12 26338148 D708N
DNA pol
UL30
HSV-2 Infection
R
View
13 26338148 A869D
DNA pol
UL30
HSV-2 Infection
R
View
14 26338148 A879V
DNA pol
UL30
HSV-2 Infection
R
View
15 26338148 M910I
DNA pol
UL30
HSV-2 Infection
R
View
16 26338148 K913M
DNA pol
UL30
HSV-2 Infection
R
View
17 26338148 R1025H
DNA pol
UL30
HSV-2 Infection
R
View
18 26338148 A1209V
DNA pol
UL30
HSV-2 Infection
R
View
19 26338148 R1230Q
DNA pol
UL30
HSV-2 Infection
R
View
20 26338148 682delED
DNA pol
UL30
HSV-2 Infection
R
View
21 26338148 684insED
DNA pol
UL30
HSV-2 Infection
D
R
View
22 26338148 686insGD
DNA pol
UL30
HSV-2 Infection
R
View
23 26338148 1112insAPGDEPA
DNA pol
UL30
HSV-2 Infection
R
View
24 26338148 A232T
DNA pol
UL30
HSV-2 Infection
R
View
25 26338148 A36G
DNA pol
UL30
HSV-2 Infection
R
View
26 26338148 E682G
DNA pol
UL30
HSV-2 Infection
R
View
27 26338148 G12R
DNA pol
UL30
HSV-2 Infection
R
View
28 26338148 T801P
DNA pol
UL30
HSV-2 Infection
R
View
29 1329374 520delC
TK
UL23
HSV-2 Infection
D
C
View
30 8392322 S182N
TK
UL23
HSV-2 Infection
D
View
31 26338148 G39E
TK
UL23
HSV-2 Infection
R
View
32 26338148 L140F
TK
UL23
HSV-2 Infection
R
View
33 26338148 A157T
TK
UL23
HSV-2 Infection
R
View
34 26338148 G150D
TK
UL23
HSV-2 Infection
R
View
35 26338148 L342W
TK
UL23
HSV-2 Infection
R
View
36 26338148 N78D
TK
UL23
HSV-2 Infection
R
View
37 26338148 R248W
TK
UL23
HSV-2 Infection
R
View
38 26338148 T131M
TK
UL23
HSV-2 Infection
R
View
39 37632051 R26H
UL23
UL23
HSV-2 Infection
R
C
L
View
40 37632051 A27T
UL23
UL23
HSV-2 Infection
R
C
L
View
41 37632051 S29A
UL23
UL23
HSV-2 Infection
R
C
L
View
42 37632051 G39E
UL23
UL23
HSV-2 Infection
R
C
L
View
43 37632051 N78D
UL23
UL23
HSV-2 Infection
R
C
L
View
44 37632051 L140F
UL23
UL23
HSV-2 Infection
R
C
L
View
45 37632051 T159I
UL23
UL23
HSV-2 Infection
R
C
L
View
46 37632051 A215T
UL23
UL23
HSV-2 Infection
R
C
L
View
47 37632051 R220K
UL23
UL23
HSV-2 Infection
R
C
L
View
48 37632051 S38A
UL23
UL23
HSV-2 Infection
R
C
L
View
49 37632051 A219V
UL23
UL23
HSV-2 Infection
R
C
L
View
50 37632051 R294H
UL23
UL23
HSV-2 Infection
R
C
L
View
51 37632051 R294S
UL23
UL23
HSV-2 Infection
R
C
L
View
52 37632051 I359V
UL23
UL23
HSV-2 Infection
R
C
L
View
53 37632051 A9T
UL30
UL30
HSV-2 Infection
R
C
L
View
54 37632051 P15S
UL30
UL30
HSV-2 Infection
R
C
L
View
55 37632051 C40W
UL30
UL30
HSV-2 Infection
R
C
L
View
56 37632051 L60P
UL30
UL30
HSV-2 Infection
R
C
L
View
57 37632051 E139K
UL30
UL30
HSV-2 Infection
R
C
L
View
58 37632051 D676G
UL30
UL30
HSV-2 Infection
R
C
L
View
59 37632051 E678G
UL30
UL30
HSV-2 Infection
R
C
L
View
60 37632051 T801P
UL30
UL30
HSV-2 Infection
R
C
L
View
61 37632051 A1000T
UL30
UL30
HSV-2 Infection
R
C
L
View
62 37632051 P138H
UL30
UL30
HSV-2 Infection
R
C
L
View
63 37632051 E191K
UL30
UL30
HSV-2 Infection
R
C
L
View
64 37632051 684_685delGD
UL30
UL30
HSV-2 Infection
R
C
L
View
65 37632051 D716A
UL30
UL30
HSV-2 Infection
R
C
L
View
66 37632051 Q792R
UL30
UL30
HSV-2 Infection
R
C
L
View
67 37632051 I1033V
UL30
UL30
HSV-2 Infection
R
C
L
View
68 37632051 A1065T
UL30
UL30
HSV-2 Infection
R
C
L
View
69 27056950 A1001G
UL5
UL5
HSV-2 Infection
R
S
View
70 27056950 A739T
UL5
UL5
HSV-2 Infection
R
S
View
71 27056950 C1281T
UL5
UL5
HSV-2 Infection
R
S
View
72 27056950 C996T
UL5
UL5
HSV-2 Infection
R
S
View
73 27056950 D513N
UL5
UL5
HSV-2 Infection
R
S
View
74 27056950 G879A
UL5
UL5
HSV-2 Infection
R
S
View
75 27056950 H334R
UL5
UL5
HSV-2 Infection
R
S
View
76 27056950 I763V
UL5
UL5
HSV-2 Infection
R
S
View
77 27056950 R415H
UL5
UL5
HSV-2 Infection
R
S
View
78 27056950 S458G
UL5
UL5
HSV-2 Infection
R
S
View
79 27056950 S605P
UL5
UL5
HSV-2 Infection
R
S
View
80 27056950 S689T
UL5
UL5
HSV-2 Infection
R
S
View
81 27056950 T1965G
UL5
UL5
HSV-2 Infection
R
S
View
82 27056950 T2100C
UL5
UL5
HSV-2 Infection
R
S
View
83 27056950 Y573H
UL5
UL5
HSV-2 Infection
R
S
View
84 27056950 G1053A
UL5
UL5
HSV-2 Infection
R
S
View
85 27056950 A578V
UL52
UL52
HSV-2 Infection
R
S
View
86 27056950 A837G
UL52
UL52
HSV-2 Infection
R
S
View
87 27056950 D58N
UL52
UL52
HSV-2 Infection
R
S
View
88 27056950 D704G
UL52
UL52
HSV-2 Infection
R
S
View
89 27056950 E101K
UL52
UL52
HSV-2 Infection
R
S
View
90 27056950 E719A
UL52
UL52
HSV-2 Infection
R
S
View
91 27056950 E9G
UL52
UL52
HSV-2 Infection
R
S
View
92 27056950 G218A
UL52
UL52
HSV-2 Infection
R
S
View
93 27056950 G312R
UL52
UL52
HSV-2 Infection
R
S
View
94 27056950 G334S
UL52
UL52
HSV-2 Infection
R
S
View
95 27056950 G430A
UL52
UL52
HSV-2 Infection
R
S
View
96 27056950 G653C
UL52
UL52
HSV-2 Infection
R
S
View
97 27056950 L600P
UL52
UL52
HSV-2 Infection
R
S
View
98 27056950 N1020H
UL52
UL52
HSV-2 Infection
R
S
View
99 27056950 R119H
UL52
UL52
HSV-2 Infection
R
S
View
100 27056950 R331H
UL52
UL52
HSV-2 Infection
R
S
View
101 27056950 R414S
UL52
UL52
HSV-2 Infection
R
S
View
102 27056950 R424M
UL52
UL52
HSV-2 Infection
R
S
View
103 27056950 R440C
UL52
UL52
HSV-2 Infection
R
S
View
104 27056950 S459P
UL52
UL52
HSV-2 Infection
R
S
View
105 27056950 S57P
UL52
UL52
HSV-2 Infection
R
S
View
106 27056950 S697L
UL52
UL52
HSV-2 Infection
R
S
View
107 27056950 T169C
UL52
UL52
HSV-2 Infection
R
S
View
108 27056950 T25A
UL52
UL52
HSV-2 Infection
R
S
View
109 27056950 T2862C
UL52
UL52
HSV-2 Infection
R
S
View
110 27056950 T495S
UL52
UL52
HSV-2 Infection
R
S
View
111 27056950 T518A
UL52
UL52
HSV-2 Infection
R
S
View
112 27056950 V144I
UL52
UL52
HSV-2 Infection
R
S
View
113 27056950 G2649A
UL52
UL52
HSV-2 Infection
R
S
View
114 27056950 C2676T
UL52
UL52
HSV-2 Infection
R
S
View
115 35973907 R628C
DNA pol
UL30
Herpes genitalis
C
View
116 35973907 C625R
DNA pol
UL30
Herpes genitalis
D
C
View
117 35973907 W89G
TK
UL23
Herpes genitalis
D
C
View
118 35271913 A27T
TK
UL23
Herpes genitalis
L
View
119 35271913 G39E
TK
UL23
Herpes genitalis
L
View
120 35271913 G39K
TK
UL23
Herpes genitalis
L
View
121 35271913 L140F
TK
UL23
Herpes genitalis
L
View
122 35271913 L263P
TK
UL23
Herpes genitalis
L
View
123 35271913 M70R
TK
UL23
Herpes genitalis
L
View
124 35271913 N78D
TK
UL23
Herpes genitalis
L
View
125 35271913 P75S
TK
UL23
Herpes genitalis
L
View
126 35271913 R18C
TK
UL23
Herpes genitalis
L
View
127 35271913 R220K
TK
UL23
Herpes genitalis
L
View
128 35271913 R26H
TK
UL23
Herpes genitalis
L
View
129 35271913 R284S
TK
UL23
Herpes genitalis
L
View
130 35271913 S29A
TK
UL23
Herpes genitalis
L
View
131 35271913 T159I
TK
UL23
Herpes genitalis
L
View
132 35271913 C52T
TK
UL23
Herpes genitalis
L
View
133 35271913 G77A
TK
UL23
Herpes genitalis
L
View
134 35271913 G79A
TK
UL23
Herpes genitalis
L
View
135 35271913 T85G
TK
UL23
Herpes genitalis
L
View
136 35271913 G116A
TK
UL23
Herpes genitalis
L
View
137 35271913 G115A+G116A
TK
UL23
Herpes genitalis
L
View
138 35271913 T209G
TK
UL23
Herpes genitalis
L
View
139 35271913 C223T
TK
UL23
Herpes genitalis
L
View
140 35271913 A232G
TK
UL23
Herpes genitalis
L
View
141 35271913 G420T
TK
UL23
Herpes genitalis
L
View
142 35271913 C476T
TK
UL23
Herpes genitalis
L
View
143 35271913 G659A
TK
UL23
Herpes genitalis
L
View
144 35271913 T788C
TK
UL23
Herpes genitalis
L
View
145 35271913 C850A
TK
UL23
Herpes genitalis
L
View
146 29186456 M789T
DNA pol
UL30
Cell line
D
R
View
147 29186456 A724V
DNA pol
UL30
Cell line
D
R
View
148 29186456 N820S
DNA pol
UL30
Cell line
R
View
149 29186456 K533E
DNA pol
UL30
Cell line
D
R
View
150 29186456 A606V
DNA pol
UL30
Cell line
D
R
View
151 29186456 C625R
DNA pol
UL30
Cell line
D
R
View
152 29186456 R628C
DNA pol
UL30
Cell line
D
R
View
153 29186456 S725G
DNA pol
UL30
Cell line
D
R
View
154 29186456 S729N
DNA pol
UL30
Cell line
D
R
View
155 29186456 I731F
DNA pol
UL30
Cell line
D
R
View
156 29186456 Q732R
DNA pol
UL30
Cell line
D
R
View
157 29186456 M789K
DNA pol
UL30
Cell line
D
R
View
158 29186456 V818A
DNA pol
UL30
Cell line
D
R
View
159 29186456 Y823C
DNA pol
UL30
Cell line
D
R
View
160 29186456 R847C
DNA pol
UL30
Cell line
D
R
View
161 29186456 F923L
DNA pol
UL30
Cell line
D
R
View
162 29186456 T934A
DNA pol
UL30
Cell line
D
R
View
163 29186456 R964H
DNA pol
UL30
Cell line
D
R
View
164 17928351 C531T
gB
UL27
Cell line
D
R
S
View
165 17928351 A2051G
gB
UL27
Cell line
D
R
S
View
166 17928351 E662G
gB
UL27
Cell line
D
R
S
View
167 17928351 T2441C
gB
UL27
Cell line
D
R
S
View
168 17928351 L792P
gB
UL27
Cell line
D
R
S
View
169 17928351 A794C
gB
UL27
Cell line
D
R
S
View
170 17928351 N243T
gB
UL27
Cell line
D
R
S
View
171 17928351 C798T
gB
UL27
Cell line
D
R
S
View
172 17928351 G2531A
gB
UL27
Cell line
D
R
S
View
173 17928351 R822Q
gB
UL27
Cell line
D
R
S
View
174 17928351 T1123C
gB
UL27
Cell line
D
R
S
View
175 17928351 Y353H
gB
UL27
Cell line
D
R
S
View
176 17928351 C129A
gB
UL27
Cell line
D
R
S
View
177 17928351 N21K
gB
UL27
Cell line
D
R
S
View
178 17928351 G1636A
gB
UL27
Cell line
D
R
S
View
179 17928351 A524T
gB
UL27
Cell line
D
R
S
View
180 17928351 C1070T
gB
UL27
Cell line
D
R
S
View
181 17928351 A335V
gB
UL27
Cell line
D
R
S
View
182 17928351 C1203T
gB
UL27
Cell line
D
R
S
View
183 17928351 G490C
gC
UL44
Cell line
D
R
S
View
184 17928351 A164P
gC
UL44
Cell line
D
R
S
View
185 17928351 G957A
gC
UL44
Cell line
D
R
S
View
186 17928351 C1383T
gC
UL44
Cell line
D
R
S
View
187 17928351 T593C
gC
UL44
Cell line
D
R
S
View
188 17928351 L198P
gC
UL44
Cell line
D
R
S
View
189 17928351 C63T
gC
UL44
Cell line
D
R
S
View
190 17928351 A155G
gD
US6
Cell line
D
R
S
View
191 17928351 Q27R
gD
US6
Cell line
D
R
S
View
192 17928351 G534A
gD
US6
Cell line
D
R
S
View
193 17928351 M148I
gD
US6
Cell line
D
R
S
View
194 17928351 G1473A
gE
US8
Cell line
D
R
S
View
195 17928351 C648T
gE
US8
Cell line
D
R
S
View
196 17928351 G1255A
gE
US8
Cell line
D
R
S
View
197 17928351 G419R
gE
US8
Cell line
D
R
S
View
198 17928351 1655delC
gG
US4
Cell line
D
R
S
I
View
199 17928351 1341delC
gG
US4
Cell line
D
R
S
I
View
200 17928351 624dupC
gG
US4
Cell line
D
R
S
I
View
201 17928351 268dupG
gG
US4
Cell line
D
R
S
I
View
202 17928351 1593delC
gG
US4
Cell line
D
R
S
I
View
203 17928351 1857delC
gG
US4
Cell line
D
R
S
I
View
204 17928351 C1740T
gG
US4
Cell line
D
R
S
I
View
205 17928351 C555T
gG
US4
Cell line
D
R
S
I
View
206 17928351 783delC
gG
US4
Cell line
D
R
S
I
View
207 17928351 C181T
gK
UL53
Cell line
D
R
S
View
208 17928351 G840A
gK
UL53
Cell line
D
R
S
View
209 17928351 G235A
gK
UL53
Cell line
D
R
S
View
210 17928351 A79T
gK
UL53
Cell line
D
R
S
View
211 2829709 G668A
TK
UL23
Cell line
D
View
212 2829709 R223H
TK
UL23
Cell line
D
View
213 2829709 Ala73fs*86
TK
UL23
Cell line
D
View
214 2829709 439del
TK
UL23
Cell line
D
View
215 23041200 S66P
TK
UL23
Cell line
D
R
View
216 23041200 A72S
TK
UL23
Cell line
D
R
View
217 23041200 I101S
TK
UL23
Cell line
D
R
View
218 23041200 M183I
TK
UL23
Cell line
D
R
View
219 29427675 G25A
TK
UL23
Cell line
View
220 29427675 G39E
TK
UL23
Cell line
View
221 29427675 Y53N
TK
UL23
Cell line
D
View
222 29427675 T131M
TK
UL23
Cell line
View
223 29427675 Y133F
TK
UL23
Cell line
View
224 29427675 G150D
TK
UL23
Cell line
View
225 29427675 A157T
TK
UL23
Cell line
View
226 29427675 R221H
TK
UL23
Cell line
D
View
227 29427675 R248W
TK
UL23
Cell line
View
228 29427675 L342W
TK
UL23
Cell line
View
229 29899106 S18A
UL13
UL13
Cell line
T
View
230 29899106 S18D
UL13
UL13
Cell line
T
View
231 29899106 S91A
UL13
UL13
Cell line
T
View
232 29899106 K176M
UL13
UL13
Cell line
T
View
233 17928351 C730T
UL24
UL24
Cell line
D
R
S
View
234 17928351 P244S
UL24
UL24
Cell line
D
R
S
View
235 17928351 C173T
UL24
UL24
Cell line
D
R
S
View
236 17928351 T58M
UL24
UL24
Cell line
D
R
S
View
237 17928351 C500T
UL24
UL24
Cell line
D
R
S
View
238 17928351 T167M
UL24
UL24
Cell line
D
R
S
View
239 17928351 G88A
UL24
UL24
Cell line
D
R
S
View
240 17928351 V30M
UL24
UL24
Cell line
D
R
S
View
241 27334584 D215N
UL41
UL41
Cell line
View
242 22687623 K355N
UL5
UL5
Cell line
D
View
243 22687623 K451R
UL5
UL5
Cell line
D
View
Contents
Description

The table shows all curated mutation sites of HSV2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.