Gene Name	ANKS1B
Gene ID	56899
Gene Full Name	ankyrin repeat and sterile alpha motif domain containing 1B
Gene Alias	AIDA|AIDA-1|ANKS2|EB-1|EB1|cajalin-2
Transcripts	ENSG00000185046
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Plasma membrane;
Membrane Info	Predicted intracellular proteins
Uniport_ID	Q7Z6G8
HGNC ID	HGNC:24600
OMIM ID	607815
Summary	This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5005622	chr12	1	0	0	1	View
5008005	chr12	4	3	0	7	View
5010274	chr12	1	0	0	1	View
5010338	chr12	5	0	0	5	View
5014896	chr12	10	18	2	30	View
5017081	chr12	0	0	0	0	View
5017082	chr12	2	1	0	3	View
5017083	chr12	1	1	0	2	View
5017084	chr12	1	4	0	5	View
5017085	chr12	12	2	0	14	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
M   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Methylation profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE183048 - ANKS1B peak across samples

Peak Plot

> Dataset: GSE143026 - ANKS1B peak across samples

Peak Plot