Gene Name	BRSK1
Gene ID	84446
Gene Full Name	BR serine/threonine kinase 1
Gene Alias	SAD-B|hSAD1
Transcripts	ENSG00000160469
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Cell Junctions;
Membrane Info	Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8TDC3
HGNC ID	HGNC:18994
OMIM ID	609235
Summary	Enables magnesium ion binding activity and tau-protein kinase activity. Involved in mitotic G2 DNA damage checkpoint signaling and protein phosphorylation. Acts upstream of or within G2/M transition of mitotic cell cycle; peptidyl-serine phosphorylation; and response to UV. Located in cell junction; cytoplasm; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5001208	chr19	11	7	26	44	View
5001622	chr19	24	3	0	27	View
5001699	chr19	22	3	0	25	View
5002415	chr19	11	0	0	11	View
5002499	chr19	11	0	0	11	View
5002579	chr19	10	0	0	10	View
5003881	chr19	1	0	1	2	View
5014051	chr19	13	0	0	13	View
5014052	chr19	33	8	2	43	View
5014053	chr19	33	8	2	43	View
5015400	chr19	19	10	38	67	View
5015401	chr19	13	0	0	13	View
5015402	chr19	33	8	2	43	View
5015403	chr19	33	8	2	43	View

Data ID	Experiment type	Sample number	Platform
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
E   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Expression profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: TCGA_CESC - BRSK1 expression across samples

Volcano Plot

Bar Plot