Gene Name	CADM2
Gene ID	253559
Gene Full Name	cell adhesion molecule 2
Gene Alias	IGSF4D|NECL3|Necl-3|SynCAM 2|SynCAM-2|synCAM2
Transcripts	ENSG00000175161
Virus	HPV
Gene Type	protein-coding
HPA Location Info
Membrane Info	Predicted membrane proteins
Uniport_ID	Q8N3J6
HGNC ID	HGNC:29849
OMIM ID	609938
Summary	This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5002897	chr3	6	1	0	7	View
5003726	chr3	1	0	1	2	View
5006749	chr3	5	0	0	5	View
5006750	chr3	0	0	0	0	View
5006751	chr3	1	2	0	3	View
5006752	chr3	0	0	0	0	View
5011900	chr3	2	0	1	3	View
5016747	chr3	0	0	0	0	View
5016748	chr3	6	1	12	19	View
5016749	chr3	6	1	12	19	View
5016750	chr3	7	174	2	183	View
5017497	chr3	39	4	0	43	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
E   M   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Expression profiling
• Methylation profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: TCGA_CESC - CADM2 expression across samples

Volcano Plot

Bar Plot