Gene Information
|
Gene Name
|
CHRM2 |
|
Gene ID
|
1129
|
|
Gene Full Name
|
cholinergic receptor muscarinic 2 |
|
Gene Alias
|
HM2 |
|
Transcripts
|
ENSG00000181072
|
|
Virus
|
HPV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Nucleoli, Golgi apparatus, Primary cilium, Basal body; 
|
|
Membrane Info
|
Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins |
|
Uniport_ID
|
P08172
|
|
HGNC ID
|
HGNC:1951
|
|
OMIM ID
|
118493 |
|
Summary
|
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] |
Target gene [CHRM2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5011069 |
chr7 |
0 |
0 |
0 |
0 |
View |
| 5011097 |
chr7 |
2 |
12 |
1 |
15 |
View |
| 5016293 |
chr7 |
16 |
8 |
17 |
41 |
View |
Target gene [CHRM2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE169622
|
Methylation profiling (Array) |
9 |
Infinium MethylationEPIC |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE196215
|
RNA-seq |
8 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE55542
|
Expression array |
36 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
E M TCGA_CESC
|
DNA methylation sequencing;RNA-seq |
288 |
TCGA |
|
GSE51993
|
Expression array |
48 |
Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip |
|
GSE55550
|
Expression array |
155 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
GSE165883
|
RNA-seq |
20 |
Illumina NextSeq 500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: TCGA_CESC - CHRM2 expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
HPV Target gene Detail Information
