Gene Information
|
Gene Name
|
EFNA5 |
|
Gene ID
|
1946
|
|
Gene Full Name
|
ephrin A5 |
|
Gene Alias
|
AF1|EFL5|EPLG7|GLC1M|LERK7|RAGS |
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Transcripts
|
ENSG00000184349
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Virus
|
HPV |
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Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles, Cytosol; 
|
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Membrane Info
|
Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins |
|
Uniport_ID
|
P52803
|
|
HGNC ID
|
HGNC:3225
|
|
OMIM ID
|
601535 |
|
Summary
|
Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq, Jul 2008] |
Target gene [EFNA5] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5010328 |
chr5 |
0 |
0 |
1 |
1 |
View |
| 5010329 |
chr5 |
3 |
0 |
2 |
5 |
View |
| 5010456 |
chr5 |
6 |
2 |
0 |
8 |
View |
| 5010702 |
chr5 |
8 |
7 |
0 |
15 |
View |
| 5013606 |
chr5 |
27 |
0 |
0 |
27 |
View |
| 5017684 |
chr5 |
4 |
6 |
0 |
10 |
View |
Target gene [EFNA5] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE183048
|
Chip-seq |
24 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE169622
|
Methylation profiling (Array) |
9 |
Infinium MethylationEPIC |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE196215
|
RNA-seq |
8 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
S GSE164690
|
scRNA-seq |
51 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE138080
|
Expression array |
35 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE55542
|
Expression array |
36 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_CESC
|
DNA methylation sequencing;RNA-seq |
288 |
TCGA |
|
GSE51993
|
Expression array |
48 |
Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip |
|
GSE55550
|
Expression array |
155 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
GSE165883
|
RNA-seq |
20 |
Illumina NextSeq 500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.
> Dataset: GSE164690 - Gene expression in cell subsets
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HPV Target gene Detail Information
