Gene Name	EPHA5
Gene ID	2044
Gene Full Name	EPH receptor A5
Gene Alias	CEK7|EHK-1|EHK1|EK7|HEK7|TYRO4
Transcripts	ENSG00000145242
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Golgi apparatus;Vesicles, Plasma membrane;
Membrane Info	Enzymes, Predicted membrane proteins
Uniport_ID	P54756
HGNC ID	HGNC:3389
OMIM ID	600004
Summary	This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5001064	chr4	2	38	14	54	View
5004983	chr4	0	1	0	1	View
5011111	chr4	2	0	0	2	View
5011423	chr4	0	1	0	1	View

Data ID	Experiment type	Sample number	Platform
M   GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
M   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Methylation profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE169622 - EPHA5 methylation across samples

Volcano Plot (delta beta value > 0.2 & FDR < 0.05)

Bar Plot (delta beta value > 0.2)

> Dataset: TCGA_CESC - EPHA5 methylation across samples

Volcano Plot (delta beta value > 0.2 & FDR < 0.05)

Bar Plot (delta beta value > 0.2)