Gene Information
|
Gene Name
|
GRIA3 |
|
Gene ID
|
2892
|
|
Gene Full Name
|
glutamate ionotropic receptor AMPA type subunit 3 |
|
Gene Alias
|
GLUR-C|GLUR-K3|GLUR3|GLURC|GluA3|MRX94|MRXSW|iGluR3 |
|
Transcripts
|
ENSG00000125675
|
|
Virus
|
HPV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Intracellular and membrane;
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
P42263
|
|
HGNC ID
|
HGNC:4573
|
|
OMIM ID
|
305915 |
|
Summary
|
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008] |
Target gene [GRIA3] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5005245 |
chrX |
0 |
5 |
3 |
8 |
View |
| 5005601 |
chrX |
1 |
0 |
0 |
1 |
View |
| 5005840 |
chrX |
0 |
0 |
0 |
0 |
View |
| 5008097 |
chrX |
31 |
54 |
91 |
176 |
View |
| 5008557 |
chrX |
8 |
0 |
0 |
8 |
View |
| 5010687 |
chrX |
3 |
0 |
0 |
3 |
View |
| 5012009 |
chrX |
0 |
3 |
0 |
3 |
View |
Target gene [GRIA3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE183048
|
Chip-seq |
24 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE65858
|
Expression array |
270 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE196215
|
RNA-seq |
8 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE55542
|
Expression array |
36 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_CESC
|
DNA methylation sequencing;RNA-seq |
288 |
TCGA |
|
GSE51993
|
Expression array |
48 |
Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip |
|
GSE55550
|
Expression array |
155 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
GSE165883
|
RNA-seq |
20 |
Illumina NextSeq 500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE183048 - GRIA3 peak across samples
|
Peak Plot
|
> Dataset: GSE143026 - GRIA3 peak across samples
|
Peak Plot
|
|
|