Gene Information
|
Gene Name
|
KPNA4 |
|
Gene ID
|
3840
|
|
Gene Full Name
|
karyopherin subunit alpha 4 |
|
Gene Alias
|
IPOA3|QIP1|SRP3 |
|
Transcripts
|
ENSG00000186432
|
|
Virus
|
IV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Nuclear membrane; 
|
|
Membrane Info
|
Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
O00629
|
|
HGNC ID
|
HGNC:6397
|
|
OMIM ID
|
602970 |
|
Summary
|
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008] |
Target gene [KPNA4] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
31044563 |
M105K |
NP
|
NP
|
Influenza A
|
G
R
S
I
T
|
View |
Target gene [KPNA4] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE243629
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE225706
|
Chip-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE135069
|
RNA-seq |
10 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE113702
|
Chip-seq |
52 |
Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens) |
|
GSE162632
|
scRNA-seq |
292 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE225704
|
ATAC-seq |
3 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE156060
|
Chip-seq;RNA-seq |
28 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE225706 - KPNA4 peak across samples
|
Peak Plot
|
> Dataset: GSE113702 - KPNA4 peak across samples
|
Peak Plot
|
> Dataset: GSE225704 - KPNA4 peak across samples
|
Peak Plot
|
> Dataset: GSE156060 - KPNA4 peak across samples
|
Peak Plot
|
|
|
IV Target gene Detail Information
