Gene Name	LHX5
Gene ID	64211
Gene Full Name	LIM homeobox 5
Gene Alias	-
Transcripts	ENSG00000089116
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Cytosol;Nucleoplasm, Nuclear bodies;
Membrane Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9H2C1
HGNC ID	HGNC:14216
OMIM ID	605992
Summary	This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5007632	chr12	45	8	5	58	View
5007633	chr12	25	7	38	70	View
5014908	chr12	128	31	19	178	View

Data ID	Experiment type	Sample number	Platform
M   GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
M   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Methylation profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE169622 - LHX5 methylation across samples

Volcano Plot (delta beta value > 0.2 & FDR < 0.05)

Bar Plot (delta beta value > 0.2)

> Dataset: TCGA_CESC - LHX5 methylation across samples

Volcano Plot (delta beta value > 0.2 & FDR < 0.05)

Bar Plot (delta beta value > 0.2)