Gene Information
|
Gene Name
|
LRRC3B |
|
Gene ID
|
116135
|
|
Gene Full Name
|
leucine rich repeat containing 3B |
|
Gene Alias
|
LRP15 |
|
Transcripts
|
ENSG00000179796
|
|
Virus
|
HPV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q96PB8
|
|
HGNC ID
|
HGNC:28105
|
|
OMIM ID
|
618996 |
|
Summary
|
The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015] |
Target gene [LRRC3B] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5006482 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 5006573 |
chr3 |
1 |
0 |
0 |
1 |
View |
| 5009998 |
chr3 |
0 |
5 |
0 |
5 |
View |
Target gene [LRRC3B] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE169622
|
Methylation profiling (Array) |
9 |
Infinium MethylationEPIC |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE196215
|
RNA-seq |
8 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE55542
|
Expression array |
36 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
E M TCGA_CESC
|
DNA methylation sequencing;RNA-seq |
288 |
TCGA |
|
GSE51993
|
Expression array |
48 |
Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip |
|
GSE55550
|
Expression array |
155 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
GSE165883
|
RNA-seq |
20 |
Illumina NextSeq 500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: TCGA_CESC - LRRC3B expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
HPV Target gene Detail Information
