HPV Target gene Detail Information

> MYOC Gene Search Result


Gene Information
Gene Name MYOC
Gene ID 4653
Gene Full Name myocilin
Gene Alias GLC1A|GPOA|JOAG|JOAG1|TIGR
Transcripts ENSG00000034971
Virus HPV
Gene Type protein-coding
HPA Location Info Secreted to extracellular matrix;
Membrane Info Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID Q99972
HGNC ID HGNC:7610
OMIM ID 601652
Summary MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008]
Target gene [MYOC] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5007121 chr1 2 17 1 20 View
5012417 chr1 26 18 1 45 View
5012418 chr1 15 2 1 18 View
5012419 chr1 14 2 1 17 View
5012420 chr1 14 2 1 17 View
5012421 chr1 8 2 0 10 View
5012422 chr1 51 9 0 60 View
5012423 chr1 51 9 0 60 View
5012424 chr1 70 15 1 86 View
5012425 chr1 72 15 1 88 View

Target gene [MYOC] related to Omics data
Data ID Experiment type Sample number Platform
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE143026 - MYOC peak across samples

Peak Plot