HPV Target gene Detail Information

> PAPPA2 Gene Search Result


Gene Information
Gene Name PAPPA2
Gene ID 60676
Gene Full Name pappalysin 2
Gene Alias PAPP-A2|PAPP-E|PAPPE|PLAC3|SSDA
Transcripts ENSG00000116183
Virus HPV
Gene Type protein-coding
HPA Location Info Endoplasmic reticulum, Vesicles;Secreted in female reproductive system;
Membrane Info Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID Q9BXP8
HGNC ID HGNC:14615
OMIM ID 619485
Summary This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Target gene [PAPPA2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5004155 chr1 0 1 0 1 View
5010666 chr1 16 13 0 29 View
5014642 chr1 0 0 0 0 View

Target gene [PAPPA2] related to Omics data
Data ID Experiment type Sample number Platform
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
E
  TCGA_CESC 		DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: TCGA_CESC - PAPPA2 expression across samples

Volcano Plot

Bar Plot