HPV Target gene Detail Information

> PPFIA2 Gene Search Result


Gene Information
Gene Name PPFIA2
Gene ID 8499
Gene Full Name PTPRF interacting protein alpha 2
Gene Alias -
Transcripts ENSG00000139220
Virus HPV
Gene Type protein-coding
HPA Location Info
Membrane Info Predicted intracellular proteins
Uniport_ID O75334
HGNC ID HGNC:9246
OMIM ID 603143
Summary The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Target gene [PPFIA2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5004917 chr12 20 764 47 831 View
5005689 chr12 8 14 0 22 View
5006519 chr12 2 0 0 2 View
5006583 chr12 0 0 0 0 View
5006652 chr12 0 1 0 1 View
5008351 chr12 2 0 0 2 View
5010186 chr12 2 2 1 5 View
5014890 chr12 17 1 1 19 View

Target gene [PPFIA2] related to Omics data
Data ID Experiment type Sample number Platform
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
M
  TCGA_CESC 		DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE143026 - PPFIA2 peak across samples

Peak Plot