MCV Target gene Detail Information

> PTP4A2 Gene Search Result


Gene Information
Gene Name PTP4A2
Gene ID 8073
Gene Full Name protein tyrosine phosphatase 4A2
Gene Alias HH13|HH7-2|HU-PP-1|OV-1|PRL-2|PRL2|PTP4A|PTPCAAX2|ptp-IV1a|ptp-IV1b
Transcripts ENSG00000184007
Virus MCV
Gene Type protein-coding
HPA Location Info
Membrane Info Enzymes, Predicted intracellular proteins
Uniport_ID Q12974
HGNC ID HGNC:9635
OMIM ID 601584
Summary The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
Target gene [PTP4A2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
7000001 chr1 551 1257 85 1893 View
7000010 chr1 41 7 0 48 View

Target gene [PTP4A2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE147406 		Chip-seq 39 Illumina NextSeq 500 (Homo sapiens)
C
  GSE124856 		Chip-seq 8 Illumina NextSeq 500 (Homo sapiens)
GSE136867 scRNA-seq 2 Illumina NextSeq 500 (Homo sapiens)
GSE226438 scRNA-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
S
  GSE117988 		scRNA-seq 6 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE69877 		Chip-seq 10 Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE230758 		Chip-seq 20 Illumina HiSeq 2500 (Homo sapiens)
S
  GSE118056 		scRNA-seq 4 Illumina NovaSeq 6000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.


> Dataset: GSE117988 - Gene expression in cell subsets

> Dataset: GSE118056 - Gene expression in cell subsets