Gene Information
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Gene Name
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PTPRG |
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Gene ID
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5793
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Gene Full Name
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protein tyrosine phosphatase receptor type G |
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Gene Alias
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HPTPG|PTPG|R-PTP-GAMMA|RPTPG |
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Transcripts
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ENSG00000144724
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Virus
|
MCV |
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Gene Type
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protein-coding |
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HPA Location Info
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Plasma membrane; 
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Membrane Info
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Enzymes, Plasma proteins, Predicted membrane proteins |
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Uniport_ID
|
P23470
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HGNC ID
|
HGNC:9671
|
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OMIM ID
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176886 |
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Summary
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008] |
Target gene [PTPRG] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 7000002 |
chr3 |
1015 |
146 |
89 |
1250 |
View |
Target gene [PTPRG] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE147406
|
Chip-seq |
39 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE124856
|
Chip-seq |
8 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE136867
|
scRNA-seq |
2 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE226438
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE117988
|
scRNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE69877
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
C GSE230758
|
Chip-seq |
20 |
Illumina HiSeq 2500 (Homo sapiens) |
|
S GSE118056
|
scRNA-seq |
4 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.
> Dataset: GSE118056 - Gene expression in cell subsets
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MCV Target gene Detail Information
