Gene Name	RBFOX1
Gene ID	54715
Gene Full Name	RNA binding fox-1 homolog 1
Gene Alias	2BP1|A2BP1|FOX-1|FOX1|HRNBP1
Transcripts	ENSG00000078328
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Nucleoli fibrillar center, Golgi apparatus, Cytosol;
Membrane Info	Predicted intracellular proteins
Uniport_ID	Q9NWB1
HGNC ID	HGNC:18222
OMIM ID	605104
Summary	The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5001536	chr16	12	3	14	29	View
5002829	chr16	5	2	0	7	View
5003538	chr16	3	0	0	3	View
5004361	chr16	0	0	0	0	View
5005746	chr16	17	8	2	27	View
5006891	chr16	17	22	1	40	View
5006892	chr16	2	5	0	7	View
5009582	chr16	0	1	0	1	View
5009634	chr16	27	10	4	41	View
5010236	chr16	5	3	3	11	View
5010957	chr16	4	2	0	6	View
5011187	chr16	1	0	0	1	View
5011233	chr16	4	6	0	10	View
5015101	chr16	1	1	33	35	View
5017183	chr16	2	11	0	13	View
5017184	chr16	0	0	0	0	View
5017185	chr16	0	2	0	2	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE183048 - RBFOX1 peak across samples

Peak Plot

> Dataset: GSE143026 - RBFOX1 peak across samples

Peak Plot