Gene Information
|
Gene Name
|
RIGI |
|
Gene ID
|
23586
|
|
Gene Full Name
|
RNA sensor RIG-I |
|
Gene Alias
|
DDX58|RIG-I|RIG1|RLR-1|SGMRT2 |
|
Transcripts
|
ENSG00000107201
|
|
Virus
|
SARS-CoV-2 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
O95786
|
|
HGNC ID
|
HGNC:19102
|
|
OMIM ID
|
609631 |
|
Summary
|
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020] |
Target gene [RIGI] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [RIGI] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE152641
|
RNA-seq |
86 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE211934
|
RNA-seq |
8 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E GSE163959
|
RNA-seq |
48 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE163623
|
Chip-seq |
5 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE283771
|
RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE167075
|
MeRIP-seq;RNA-seq |
16 |
Illumina NovaSeq 6000 (Homo sapiens; Severe acute respiratory syndrome coronavirus 2);Illumina NovaSeq 6000 (Chlorocebus aethiops; Severe acute respiratory syndrome coronavirus 2) |
|
GSE166253
|
RNA-seq |
26 |
HiSeq X Ten (Homo sapiens) |
|
E GSE199816
|
RNA-seq |
27 |
DNBSEQ-G400 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE163959 - RIGI expression across samples
|
Volcano Plot
|
Bar Plot
|
> Dataset: GSE199816 - RIGI expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
SARS-CoV-2 Target gene Detail Information
