HPV Target gene Detail Information

> RLN1 Gene Search Result


Gene Information
Gene Name RLN1
Gene ID 6013
Gene Full Name relaxin 1
Gene Alias H1|H1RLX|RLXH1|bA12D24.3.1|bA12D24.3.2
Transcripts ENSG00000107018
Virus HPV
Gene Type protein-coding
HPA Location Info Secreted to blood;
Membrane Info Plasma proteins, Predicted secreted proteins
Uniport_ID P04808
HGNC ID HGNC:10026
OMIM ID 179730
Summary Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]
Target gene [RLN1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5013851 chr9 55 6 0 61 View
5013852 chr9 55 6 0 61 View
5013853 chr9 2 1 0 3 View
5017826 chr9 13 3 0 16 View
5017827 chr9 12 0 0 12 View
5017846 chr9 1236 2672 1943 5851 View
5017847 chr9 1200 2581 1926 5707 View
5017848 chr9 2036 402 241 2679 View
5017849 chr9 19 0 0 19 View
5017851 chr9 156 57 77 290 View
5017857 chr9 3 33 3 39 View

Target gene [RLN1] related to Omics data
Data ID Experiment type Sample number Platform
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE143026 - RLN1 peak across samples

Peak Plot