Gene symbol: Gbp2b

Also known as: Gbp1; Mpa1; Gbp-1; LIMIT; Mag-1; Mpa-1

Organism: Mus musculus

Summary: Enables GMP binding activity. Acts upstream of or within adhesion of symbiont to host; cellular response to interferon-beta; and defense response to other organism. Located in cytoplasmic vesicle and symbiont-containing vacuole membrane. Orthologous to human GBP2 (guanylate binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 14468 Ensembl:ENSMUSG00000040264 AllianceGenome:MGI:95666


GO Annotation


Category Term ID Term description
Process GO:0001562 Response to protozoan
Process GO:0002376 Immune system process
Process GO:0006950 Response to stress
Process GO:0006952 Defense response
Process GO:0006955 Immune response
Process GO:0009605 Response to external stimulus
Process GO:0009607 Response to biotic stimulus
Process GO:0009615 Response to virus
Process GO:0009617 Response to bacterium
Process GO:0009987 Cellular process
Process GO:0010033 Response to organic substance
Process GO:0034097 Response to cytokine
Process GO:0034341 Response to interferon-gamma
Process GO:0035456 Response to interferon-beta
Process GO:0035458 Cellular response to interferon-beta
Process GO:0042221 Response to chemical
Process GO:0042742 Defense response to bacterium
Process GO:0042832 Defense response to protozoan
Process GO:0043207 Response to external biotic stimulus
Process GO:0044403 Biological process involved in symbiotic interaction
Process GO:0044406 Adhesion of symbiont to host
Process GO:0044419 Biological process involved in interspecies interaction between organisms
Process GO:0045087 Innate immune response
Process GO:0050830 Defense response to Gram-positive bacterium
Process GO:0050896 Response to stimulus
Process GO:0051607 Defense response to virus
Process GO:0051701 Biological process involved in interaction with host
Process GO:0051707 Response to other organism
Process GO:0051716 Cellular response to stimulus
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071310 Cellular response to organic substance
Process GO:0071345 Cellular response to cytokine stimulus
Process GO:0071346 Cellular response to interferon-gamma
Process GO:0098542 Defense response to other organism
Process GO:0140546 Defense response to symbiont
Component GO:0000139 Golgi membrane
Component GO:0005576 Extracellular region
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005654 Nucleoplasm
Component GO:0005737 Cytoplasm
Component GO:0005794 Golgi apparatus
Component GO:0005829 Cytosol
Component GO:0005886 Plasma membrane
Component GO:0012505 Endomembrane system
Component GO:0016020 Membrane
Component GO:0018995 Host cellular component
Component GO:0020003 Symbiont-containing vacuole
Component GO:0020005 Symbiont-containing vacuole membrane
Component GO:0030430 Host cell cytoplasm
Component GO:0031090 Organelle membrane
Component GO:0031410 Cytoplasmic vesicle
Component GO:0031974 Membrane-enclosed lumen
Component GO:0031981 Nuclear lumen
Component GO:0031982 Vesicle
Component GO:0033643 Host cell part
Component GO:0033646 Host intracellular part
Component GO:0033655 Host cell cytoplasm part
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043230 Extracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043233 Organelle lumen
Component GO:0043656 Host intracellular region
Component GO:0043657 Host cell
Component GO:0048471 Perinuclear region of cytoplasm
Component GO:0065010 Extracellular membrane-bounded organelle
Component GO:0070013 Intracellular organelle lumen
Component GO:0071944 Cell periphery
Component GO:0097708 Intracellular vesicle
Component GO:0098588 Bounding membrane of organelle
Component GO:0110165 Cellular anatomical entity
Function GO:0000166 Nucleotide binding
Function GO:0003824 Catalytic activity
Function GO:0003924 GTPase activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005525 GTP binding
Function GO:0016462 Pyrophosphatase activity
Function GO:0016787 Hydrolase activity
Function GO:0016817 Hydrolase activity, acting on acid anhydrides
Function GO:0016818 Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Function GO:0017076 Purine nucleotide binding
Function GO:0017111 Nucleoside-triphosphatase activity
Function GO:0019001 Guanyl nucleotide binding
Function GO:0019002 GMP binding
Function GO:0032553 Ribonucleotide binding
Function GO:0032555 Purine ribonucleotide binding
Function GO:0032561 Guanyl ribonucleotide binding
Function GO:0035639 Purine ribonucleoside triphosphate binding
Function GO:0036094 Small molecule binding
Function GO:0042802 Identical protein binding
Function GO:0042803 Protein homodimerization activity
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0046983 Protein dimerization activity
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding

Pathway annotation


Category Term ID Term description
WikiPathways WP1253 Type II interferon signaling (IFNG)
KEGG mmu04621 NOD-like receptor signaling pathway

Expression profile of Gbp2b in omics data



ID GSE109165
Title Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway
Organism Mus musculus
GSM Sample info Characteristics Value
GSM2934457 WT_Naive_1 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: naïve 57.0
GSM2934458 WT_Naive_2 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: naïve 172.0
GSM2934459 WT_Naive_3 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: naïve 87.0
GSM2934460 WT_Naive_4 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: naïve 110.0
GSM2934461 KO_Naive_1 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: naïve 138.0
GSM2934462 KO_Naive_2 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: naïve 106.0
GSM2934463 KO_Naive_3 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: naïve 69.0
GSM2934464 KO_Naive_4 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: naïve 95.0
GSM2934465 WT_Morphine_1 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: morphine 45.0
GSM2934466 WT_Morphine_2 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: morphine 37.0
GSM2934467 WT_Morphine_3 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: morphine 85.0
GSM2934468 WT_Morphine_4 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: wildtype treatment: morphine 53.0
GSM2934469 KO_Morphine_1 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: morphine 63.0
GSM2934470 KO_Morphine_2 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: morphine 34.0
GSM2934471 KO_Morphine_3 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: morphine 41.0
GSM2934472 KO_Morphine_4 tissue: brain brain region: Periaqueductal gray region Sex: Male genotype: RGSz1 KO treatment: morphine 63.0

ID GSE125076
Title A mouse model of acute post-surgical pain
Organism Mus musculus
GSM Sample info Characteristics Value
GSM3562188 DRG_WT_sham_1 strain: C57BL/6 gender: male age: 8 weeks treatment: naïve 0.0
GSM3562189 DRG_WT_sham_2 strain: C57BL/6 gender: male age: 8 weeks treatment: naïve 3.0
GSM3562190 DRG_WT_sham_3 strain: C57BL/6 gender: male age: 8 weeks treatment: naïve 2.0
GSM3562191 DRG_WT_PSP_1 strain: C57BL/6 gender: male age: 8 weeks treatment: 24h post surgery 0.0
GSM3562192 DRG_WT_PSP_2 strain: C57BL/6 gender: male age: 8 weeks treatment: 24h post surgery 4.0
GSM3562193 DRG_WT_PSP_3 strain: C57BL/6 gender: male age: 8 weeks treatment: 24h post surgery 4.0

ID GSE126662
Title Comparison between opioid (morphine) and vehicle treatments in mouse trigeminal ganglia and nucleus accumbens
Organism Mus musculus
GSM Sample info Characteristics Value
GSM3610703 TG_M1: OIH_M1_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 1.5
GSM3610704 TG_M2: OIH_M2_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 0.5
GSM3610705 TG_M3: OIH_M3_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 1.0
GSM3610706 TG_M4: OIH_M4_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 0.0
GSM3610707 TG_M5: OIH_M5_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 0.0
GSM3610708 TG_V1: VehicleOIH_V1_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 1.0
GSM3610709 TG_V2: VehicleOIH_V2_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 0.5
GSM3610710 TG_V3: VehicleOIH_V3_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 4.0
GSM3610711 TG_V4: VehicleOIH_V4_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 2.5
GSM3610712 TG_V5: VehicleOIH_V5_Trigeminal_Ganglia tissue: Trigeminal ganglia strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 1.5
GSM3610713 NAc_M1: OIH_M1_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 0.5
GSM3610714 NAc_M2: OIH_M2_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 1.5
GSM3610715 NAc_M3: OIH_M3_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 0.0
GSM3610716 NAc_M4: OIH_M4_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 0.5
GSM3610717 NAc_M5: OIH_M5_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: OIH age: 9-12 weeks old Sex: male 0.0
GSM3610718 NAc_V1: VehicleOIH_V1_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 0.0
GSM3610719 NAc_V2: VehicleOIH_V2_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 0.5
GSM3610720 NAc_V3: VehicleOIH_V3_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 1.0
GSM3610721 NAc_V4: VehicleOIH_V4_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 0.0
GSM3610722 NAc_V5: VehicleOIH_V5_Nucleus_Accumbens tissue: Nucleus accumbens strain: C57BL/6J treatment: Vehicle age: 9-12 weeks old Sex: male 0.5

ID GSE163828
Title Regulation of electro-acupuncture(EA) and astragalus membranaceus (AM) on genes in bone marrow
Organism Mus musculus
GSM Sample info Characteristics Value
GSM4988039 BH190126-1_control tissue: bone marrow 5.33
GSM4988040 BH190126-1_treatment of astragalus membranaceus tissue: bone marrow 5.55
GSM4988041 BH190126-1_cisplatin tissue: bone marrow 5.57
GSM4988042 BH190126-1_treatment of electro-acupuncture tissue: bone marrow 5.65

ID GSE20160
Title Gene Expression Data from Prefrontal Cortex and Nucleus Accumbens from Inbred Strains of Mice
Organism Mus musculus
GSM Sample info Characteristics Value
GSM505749 129S1/SvImJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: 129S1/SvImJ 3.621
GSM505750 A/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: A/J 3.604
GSM505751 AKR/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: AKR/J 3.581
GSM505752 BALB/cByJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: BALB/cByJ 3.624
GSM505753 BTBR_T+_tf/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: BTBR_T+_tf/J 3.611
GSM505754 BUB/BnJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: BUB/BnJ 3.616
GSM505755 C3H/HeJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: C3H/HeJ 3.589
GSM505756 C57BL/6J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: C57BL/6J 3.626
GSM505757 C57BR/cdJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: C57BR/cdJ 3.63
GSM505758 C58/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: C58/J 3.625
GSM505759 CBA/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: CBA/J 3.622
GSM505760 CE/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: CE/J 3.627
GSM505761 DBA/2J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: DBA/2J 3.645
GSM505762 FVB/NJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: FVB/NJ 3.65
GSM505763 I/LnJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: I/LnJ 3.67
GSM505764 KK/HlJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: KK/HlJ 3.608
GSM505765 MA/MyJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: MA/MyJ 3.62
GSM505766 MRL_MpJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: MRL/MpJ 3.548
GSM505767 NOD/LtJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: NOD/LtJ 3.595
GSM505768 NON/LtJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: NON/LtJ 3.634
GSM505769 NZO/HILtJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: NZO/HILtJ 3.612
GSM505770 NZW_LacJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: NZW_LacJ 3.605
GSM505771 P/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: P/J 3.645
GSM505772 PL/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: PL/J 3.68
GSM505773 RIIIS/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: RIIIS/J 3.653
GSM505774 SJL/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: SJL/J 3.636
GSM505775 SM/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: SM/J 3.6
GSM505776 SWR/J_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: SWR/J 3.64
GSM505777 WSB/EiJ_Male_Frontal_Cortex gender: male tissue: Frontal Cortex strain: WSB/EiJ 3.655
GSM505778 129S1/SvImJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: 129S1/SvImJ 3.719
GSM505779 A/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: A/J 3.788
GSM505780 AKR/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: AKR/J 3.728
GSM505781 BALB/cByJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: BALB/cByJ 3.756
GSM505782 BTBR_T+_tf/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: BTBR_T+_tf/J 3.861
GSM505783 BUB/BnJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: BUB/BnJ 3.696
GSM505784 C3H/HeJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: C3H/HeJ 3.723
GSM505785 C57BL/6J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: C57BL/6J 3.756
GSM505786 C57BR/cdJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: C57BR/cdJ 3.771
GSM505787 C58/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: C58/J 3.734
GSM505788 CBA/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: CBA/J 3.704
GSM505789 CE/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: CE/J 3.741
GSM505790 DBA/2J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: DBA/2J 3.719
GSM505791 FVB/NJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: FVB/NJ 3.775
GSM505792 I/LnJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: I/LnJ 3.711
GSM505793 KK/HlJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: KK/HlJ 3.709
GSM505794 MA/MyJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: MA/MyJ 3.731
GSM505795 NOD/LtJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: NOD/LtJ 3.719
GSM505796 NON/LtJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: NON/LtJ 3.674
GSM505797 NZW/LacJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: NZW/LacJ 3.697
GSM505798 P/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: P/J 3.701
GSM505799 PL/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: PL/J 3.682
GSM505800 RIIIS/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: RIIIS/J 3.752
GSM505801 SJL/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: SJL/J 3.755
GSM505802 SM/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: SM/J 3.731
GSM505803 SWR/J_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: SWR/J 3.751
GSM505804 WSB/EiJ_Male_Nuc_Acc gender: male tissue: Nucleus Accumbens strain: WSB/EiJ 3.767

ID GSE205201
Title Hepatic responses of mice and rats to equivalent acetaminophen (APAP) insult [mouse]
Organism Mus musculus
GSM Sample info Characteristics Value
GSM6208462 Mouse_Baseline_0h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: Untreated hours after treatment: 0 6.709246
GSM6208463 Mouse_Baseline_0h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: Untreated hours after treatment: 0 6.797984
GSM6208464 Mouse_Baseline_0h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: Untreated hours after treatment: 0 6.939569
GSM6208465 Mouse_Baseline_0h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: Untreated hours after treatment: 0 6.669023
GSM6208466 Mouse_Baseline_0h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: Untreated hours after treatment: 0 7.090908
GSM6208467 Mouse_Vehicle_03h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.684029
GSM6208468 Mouse_Vehicle_03h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.582916
GSM6208469 Mouse_Vehicle_03h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.707656
GSM6208470 Mouse_Vehicle_03h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.568661
GSM6208471 Mouse_Vehicle_03h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.581945
GSM6208472 Mouse_Vehicle_06h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 7.007264
GSM6208473 Mouse_Vehicle_06h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.671457
GSM6208474 Mouse_Vehicle_06h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.761955
GSM6208475 Mouse_Vehicle_06h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.844364
GSM6208476 Mouse_Vehicle_06h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.758604
GSM6208477 Mouse_Vehicle_09h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.670751
GSM6208478 Mouse_Vehicle_09h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.601804
GSM6208479 Mouse_Vehicle_09h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.537857
GSM6208480 Mouse_Vehicle_09h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.826039
GSM6208481 Mouse_Vehicle_09h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 7.009982
GSM6208482 Mouse_Vehicle_24h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 6.961438
GSM6208483 Mouse_Vehicle_24h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 6.925315
GSM6208484 Mouse_Vehicle_24h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 7.314647
GSM6208485 Mouse_Vehicle_24h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 7.072008
GSM6208486 Mouse_Vehicle_24h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 7.237755
GSM6208487 Mouse_APAP_03h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.737006
GSM6208488 Mouse_APAP_03h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.578161
GSM6208489 Mouse_APAP_03h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.874254
GSM6208490 Mouse_APAP_03h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.724091
GSM6208491 Mouse_APAP_03h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.677979
GSM6208492 Mouse_APAP_06h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.457974
GSM6208493 Mouse_APAP_06h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.566015
GSM6208494 Mouse_APAP_06h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.542869
GSM6208495 Mouse_APAP_06h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.773459
GSM6208496 Mouse_APAP_06h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 6 7.012396
GSM6208497 Mouse_APAP_09h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.360999
GSM6208498 Mouse_APAP_09h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.380314
GSM6208499 Mouse_APAP_09h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.353284
GSM6208500 Mouse_APAP_09h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.787407
GSM6208501 Mouse_APAP_09h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.622376
GSM6208502 Mouse_APAP_24h_1 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.574769
GSM6208503 Mouse_APAP_24h_2 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.865691
GSM6208504 Mouse_APAP_24h_3 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.545838
GSM6208505 Mouse_APAP_24h_4 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.498036
GSM6208506 Mouse_APAP_24h_5 tissue: liver strain: C57Bl/6J Sex: male treatment: 300 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.352949

ID GSE223541
Title Oxycodone withdrawal induces HDAC1/2-dependent transcriptional maladaptations in the reward pathway in a murine model of peripheral nerve injury
Organism Mus musculus
GSM Sample info Characteristics Value
GSM6958536 B1 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: Sa 0.0
GSM6958537 C1 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: oxy 0.0
GSM6958538 F1 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: Sal 0.0
GSM6958539 H1 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: oxy 1.0
GSM6958540 B2 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: Sal 2.0
GSM6958541 C2 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: oxy 0.0
GSM6958542 F2 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: Sal 1.0
GSM6958543 H2 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: oxy 0.0
GSM6958544 B3 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: Sal 1.0
GSM6958545 C3 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: oxy 1.0
GSM6958546 F3 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: Sal 0.0
GSM6958547 H3 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: oxy 4.0
GSM6958548 B4 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: Sal 0.0
GSM6958549 C4 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: Sham condition: oxy 0.0
GSM6958550 F4 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: Sal 0.0
GSM6958551 H4 tissue: Brain strain: C57BL/6 Sex: male cell type: Nac genotype: SNI condition: oxy 2.0

ID GSE24829
Title Gene expression data from striatal regions of MPTP-intoxicated mouse brain by acupuncture
Organism Mus musculus
GSM Sample info Characteristics Value
GSM611081 Control mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: Control 4.24865
GSM611082 Control mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: Control 3.94272
GSM611083 MPTP-treated mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP-treated 4.40869
GSM611084 MPTP-treated mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP-treated 4.02955
GSM611085 MPTP and acupoints acupuncture-treated mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 3.90974
GSM611086 MPTP and acupoints acupuncture-treated mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 4.08218
GSM611087 MPTP and nonacupoints acupuncture-treated mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 4.19712
GSM611088 MPTP and nonacupoints acupuncture-treated mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 4.01137

ID GSE24830
Title Gene expression data from cervical spinal cord regions of MPTP-intoxicated mouse by acupuncture
Organism Mus musculus
GSM Sample info Characteristics Value
GSM611089 Control mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: Control 3.89686
GSM611090 Control mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: Control 3.25141
GSM611091 MPTP-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP-treated 3.59247
GSM611092 MPTP-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP-treated 3.49301
GSM611093 MPTP and acupoints acupuncture-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 3.9487
GSM611094 MPTP and acupoints acupuncture-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 3.93684
GSM611095 MPTP and nonacupoints acupuncture-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 3.94874
GSM611096 MPTP and nonacupoints acupuncture-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 3.78658

ID GSE24838
Title Gene expression data from brain striatal and spinal cord regions of MPTP-intoxicated mouse following acupuncture
Organism Mus musculus
GSM Sample info Characteristics Value
GSM611081 Control mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: Control 4.24865
GSM611082 Control mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: Control 3.94272
GSM611083 MPTP-treated mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP-treated 4.40869
GSM611084 MPTP-treated mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP-treated 4.02955
GSM611085 MPTP and acupoints acupuncture-treated mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 3.90974
GSM611086 MPTP and acupoints acupuncture-treated mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 4.08218
GSM611087 MPTP and nonacupoints acupuncture-treated mouse 1 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 4.19712
GSM611088 MPTP and nonacupoints acupuncture-treated mouse 2 striatal regions gender: Male strain: C57BL/6 tissue: Striatal tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 4.01137
GSM611089 Control mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: Control 3.89686
GSM611090 Control mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: Control 3.25141
GSM611091 MPTP-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP-treated 3.59247
GSM611092 MPTP-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP-treated 3.49301
GSM611093 MPTP and acupoints acupuncture-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 3.9487
GSM611094 MPTP and acupoints acupuncture-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 3.93684
GSM611095 MPTP and nonacupoints acupuncture-treated mouse 1 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 3.94874
GSM611096 MPTP and nonacupoints acupuncture-treated mouse 2 cervical spinal cord regions gender: Male strain: C57BL/6 tissue: Cervical spinal cord tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 3.78658

ID GSE26364
Title Gene expression changes in alpha GABA receptors in the mice brains after prolonged ketamine administration
Organism Mus musculus
GSM Sample info Characteristics Value
GSM647254 Saline PFC 1 strain: ICR tissue: prefrontal cortex Sex: female 3.37506
GSM647255 Saline PFC 2 strain: ICR tissue: prefrontal cortex Sex: female 3.62934
GSM647256 Ketamine PFC 1 strain: ICR tissue: prefrontal cortex Sex: female 3.60385
GSM647257 Ketamine PFC 2 strain: ICR tissue: prefrontal cortex Sex: female 3.7552

ID GSE35138
Title Gene expression data from thalamic regions of MPTP-intoxicated mouse brain by acupuncture
Organism Mus musculus
GSM Sample info Characteristics Value
GSM862520 Control mouse 1 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.69719
GSM862521 Control mouse 2 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.59248
GSM862522 MPTP-treated mouse 1 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.50415
GSM862523 MPTP-treated mouse 2 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.43183
GSM862524 MPTP and acupoints acupuncture-treated mouse 1 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.50158
GSM862525 MPTP and acupoints acupuncture-treated mouse 2 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.67037
GSM862526 MPTP and nonacupoints acupuncture-treated mouse 1 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.48275
GSM862527 MPTP and nonacupoints acupuncture-treated mouse 2 thalamic regions gender: Male strain: C57BL/6 tissue: thalamic tissues developmental stage: Adult 4.42137

ID GSE48293
Title Gene expression data from substantia nigral regions of MPTP-intoxicated mouse brain by acupuncture
Organism Mus musculus
GSM Sample info Characteristics Value
GSM1174263 Control mouse 1 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: Control 5.38768
GSM1174264 Control mouse 2 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: Control 6.58093
GSM1174265 MPTP-treated mouse 1 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: MPTP-treated 6.96737
GSM1174266 MPTP-treated mouse 2 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: MPTP-treated 6.95095
GSM1174267 MPTP and acupoints acupuncture-treated mouse 1 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 7.04617
GSM1174268 MPTP and acupoints acupuncture-treated mouse 2 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: MPTP and acupoints acupuncture-treated 6.84307
GSM1174269 MPTP and nonacupoints acupuncture-treated mouse 1 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 6.79134
GSM1174270 MPTP and nonacupoints acupuncture-treated mouse 2 substantia nigral regions gender: Male strain: C57BL/6 tissue: substantia nigral tissues developmental stage: Adult treatment: MPTP and nonacupoints acupuncture-treated 6.51336