All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Acute and Chronic Hepatitis B Virus Infection-35891356
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35891356 T184S
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
2 35891356 T411C
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
3 35891356 T513A
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
4 35891356 V173E
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
5 35891356 V173L
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
6 35891356 V47G
S
S
Acute and Chronic Hepatitis B Virus Infection
G
I
C
L
View
7 35891356 D42X
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
8 35891356 C69X
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
9 35891356 W179X
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
10 35891356 W182X
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
11 35891356 W43R
PreS1
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
12 35891356 A47S
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
13 35891356 A62G
PreS1
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
14 35891356 A7Q
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
15 35891356 A7T
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
16 35891356 C408T
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
17 35891356 C513T
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
18 35891356 C666T
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
19 35891356 D51G
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
20 35891356 F19C
S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
21 35891356 F63Y
PreS1
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
22 35891356 F8L
S
S
Acute and Chronic Hepatitis B Virus Infection
G
I
C
L
View
23 35891356 G18V
S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
24 35891356 G206A
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
25 35891356 G44E
S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
26 35891356 G625R
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
27 35891356 H51N
PreS1
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
28 35891356 H51T
PreS1
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
29 35891356 I42T
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
30 35891356 L180M
RT
P
Acute and Chronic Hepatitis B Virus Infection
D
G
C
L
View
31 35891356 M204I
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
32 35891356 M204V
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
33 35891356 M250A
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
34 35891356 M250G
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
35 35891356 M250P
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
36 35891356 M250Q
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
37 35891356 M250S
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
38 35891356 M250T
RT
P
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
39 35891356 P41L
PreS1
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
40 35891356 P47K
PreS1
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
41 35891356 Q13L
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
42 35891356 S45P
S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
43 35891356 S61L
S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
44 35891356 T134C
PreS;S
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.