All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-32543353
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 32543353 C145T
S
S
COVID-19
R
S
L
View
2 32543353 C2651T
S
S
COVID-19
R
S
L
View
3 32543353 D614G
S
S
COVID-19
R
S
L
View
4 32543353 F817L
S
S
COVID-19
R
S
L
View
5 32543353 H49Y
S
S
COVID-19
R
S
L
View
6 32543353 S884F
S
S
COVID-19
R
S
L
View
7 32543353 T2449C
S
S
COVID-19
R
S
L
View
8 32543353 L84S
ORF8
ORF8
COVID-19
R
S
L
View
9 32543353 A59D
ORF3a
ORF3a
COVID-19
R
S
L
View
10 32543353 C176A
ORF3a
ORF3a
COVID-19
R
S
L
View
11 32543353 G251V
ORF3a
ORF3a
COVID-19
R
S
L
View
12 32543353 A16577G
ORF1ab
ORF1ab
COVID-19
R
S
L
View
13 32543353 A4788G
ORF1ab
ORF1ab
COVID-19
R
S
L
View
14 32543353 C10809T
ORF1ab
ORF1ab
COVID-19
R
S
L
View
15 32543353 C14144T
ORF1ab
ORF1ab
COVID-19
R
S
L
View
16 32543353 C19547T
ORF1ab
ORF1ab
COVID-19
R
S
L
View
17 32543353 C2772T
ORF1ab
ORF1ab
COVID-19
R
S
L
View
18 32543353 C8517T
ORF1ab
ORF1ab
COVID-19
R
S
L
View
19 32543353 G21055A
ORF1ab
ORF1ab
COVID-19
R
S
L
View
20 32543353 G7019S
ORF1ab
ORF1ab
COVID-19
R
S
L
View
21 32543353 K5526R
ORF1ab
ORF1ab
COVID-19
R
S
L
View
22 32543353 P4715L
ORF1ab
ORF1ab
COVID-19
R
S
L
View
23 32543353 S6248L
ORF1ab
ORF1ab
COVID-19
R
S
L
View
24 32543353 T17459C
ORF1ab
ORF1ab
COVID-19
R
S
L
View
25 32543353 V378I
ORF1ab
ORF1ab
COVID-19
R
S
L
View
26 32543353 V5820A
ORF1ab
ORF1ab
COVID-19
R
S
L
View
27 32543353 C595T
N
N
COVID-19
R
S
L
View
28 32543353 G204R
N
N
COVID-19
R
S
L
View
29 32543353 G608A
N
N
COVID-19
R
S
L
View
30 32543353 G609A
N
N
COVID-19
R
S
L
View
31 32543353 G610C
N
N
COVID-19
R
S
L
View
32 32543353 P199S
N
N
COVID-19
R
S
L
View
33 32543353 R203K
N
N
COVID-19
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.