All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-32595354
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 32595354 A23403G
S
S
COVID-19
R
L
View
2 32595354 D614G
S
S
COVID-19
R
L
View
3 32595354 C22444T
S
S
COVID-19
R
L
View
4 32595354 C14408T
RdRp
ORF1b
COVID-19
R
L
View
5 32595354 P323L
RdRp
ORF1b
COVID-19
R
L
View
6 32595354 G25563T
ORF3a
ORF3a
COVID-19
R
L
View
7 32595354 Q57H
ORF3a
ORF3a
COVID-19
R
L
View
8 32595354 C18877T
ORF1b
ORF1b
COVID-19
R
L
View
9 32595354 C17690T
ORF1b
ORF1b
COVID-19
R
L
View
10 32595354 C3037T
ORF1a
ORF1a
COVID-19
R
L
View
11 32595354 G11083T
ORF1a
ORF1a
COVID-19
R
L
View
12 32595354 G1397A
ORF1a
ORF1a
COVID-19
R
L
View
13 32595354 C884T
ORF1a
ORF1a
COVID-19
R
L
View
14 32595354 G8653T
ORF1a
ORF1a
COVID-19
R
L
View
15 32595354 A9514G
ORF1a
ORF1a
COVID-19
R
L
View
16 32595354 C5736T
ORF1a
ORF1a
COVID-19
R
L
View
17 32595354 G9479T
ORF1a
ORF1a
COVID-19
R
L
View
18 32595354 C7765T
ORF1a
ORF1a
COVID-19
R
L
View
19 32595354 R203K
N
N
COVID-19
R
L
View
20 32595354 G204R
N
N
COVID-19
R
L
View
21 32595354 S194L
N
N
COVID-19
R
L
View
22 32595354 S188P
N
N
COVID-19
R
L
View
23 32595354 L37F
NSP6
ORF1a
COVID-19
R
L
View
24 32595354 M33I
NSP4
ORF1a
COVID-19
R
L
View
25 32595354 G309C
NSP4
ORF1a
COVID-19
R
L
View
26 32595354 A1006V
NSP3
ORF1a
COVID-19
R
L
View
27 32595354 V198I
NSP2
ORF1a
COVID-19
R
L
View
28 32595354 R27C
NSP2
ORF1a
COVID-19
R
L
View
29 32595354 T28688C
N
N
COVID-19
R
L
View
30 32595354 G28881A
N
N
COVID-19
R
L
View
31 32595354 G28882A
N
N
COVID-19
R
L
View
32 32595354 G28883C
N
N
COVID-19
R
L
View
33 32595354 C28854T
N
N
COVID-19
R
L
View
34 32595354 T28835C
N
N
COVID-19
R
L
View
35 32595354 V10A
M
M
COVID-19
R
L
View
36 32595354 C26735T
M
M
COVID-19
R
L
View
37 32595354 C26549T
M
M
COVID-19
R
L
View
38 32595354 G26720C
M
M
COVID-19
R
L
View
39 32595354 T26551C
M
M
COVID-19
R
L
View
40 32595354 S485L
NSP13
ORF1b
COVID-19
R
L
View
41 32595354 C241T
5'UTR
COVID-19
R
L
View
42 32595354 C228T
5'UTR
COVID-19
R
L
View
43 32595354 G29742T
3'UTR
COVID-19
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.