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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19All Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	33225958	A15491G	RdRp	ORF1b	COVID-19	R L	View
2	33225958	A15553G	RdRp	ORF1b	COVID-19	R L	View
3	33225958	A15593G	RdRp	ORF1b	COVID-19	R L	View
4	33225958	A15596G	RdRp	ORF1b	COVID-19	R L	View
5	33225958	A15640T	RdRp	ORF1b	COVID-19	R L	View
6	33225958	A15641C	RdRp	ORF1b	COVID-19	R L	View
7	33225958	A15647G	RdRp	ORF1b	COVID-19	R L	View
8	33225958	A15668G	RdRp	ORF1b	COVID-19	R L	View
9	33225958	A15683T	RdRp	ORF1b	COVID-19	R L	View
10	33225958	A639V	RdRp	ORF1b	COVID-19	R L	View
11	33225958	A656S	RdRp	ORF1b	COVID-19	R L	View
12	33225958	A656T	RdRp	ORF1b	COVID-19	R L	View
13	33225958	A656V	RdRp	ORF1b	COVID-19	R L	View
14	33225958	A660S	RdRp	ORF1b	COVID-19	R L	View
15	33225958	A699S	RdRp	ORF1b	COVID-19	R L	View
16	33225958	A716S	RdRp	ORF1b	COVID-19	R L	View
17	33225958	C15319T	RdRp	ORF1b	COVID-19	R L	View
18	33225958	C15324T	RdRp	ORF1b	COVID-19	R L	View
19	33225958	C15328T	RdRp	ORF1b	COVID-19	R L	View
20	33225958	C15346A	RdRp	ORF1b	COVID-19	R L	View
21	33225958	C15346T	RdRp	ORF1b	COVID-19	R L	View
22	33225958	C15352T	RdRp	ORF1b	COVID-19	R L	View
23	33225958	C15356T	RdRp	ORF1b	COVID-19	R L	View
24	33225958	C15358A	RdRp	ORF1b	COVID-19	R L	View
25	33225958	C15364A	RdRp	ORF1b	COVID-19	R L	View
26	33225958	C15368T	RdRp	ORF1b	COVID-19	R L	View
27	33225958	C15371T	RdRp	ORF1b	COVID-19	R L	View
28	33225958	C15407T	RdRp	ORF1b	COVID-19	R L	View
29	33225958	C15613T	RdRp	ORF1b	COVID-19	R L	View
30	33225958	C15619T	RdRp	ORF1b	COVID-19	R L	View
31	33225958	C15656T	RdRp	ORF1b	COVID-19	R L	View
32	33225958	C15688T	RdRp	ORF1b	COVID-19	R L	View
33	33225958	D684G	RdRp	ORF1b	COVID-19	R L	View
34	33225958	D711Y	RdRp	ORF1b	COVID-19	R L	View
35	33225958	D717Y	RdRp	ORF1b	COVID-19	R L	View
36	33225958	D736G	RdRp	ORF1b	COVID-19	R L	View
37	33225958	D738Y	RdRp	ORF1b	COVID-19	R L	View
38	33225958	E729D	RdRp	ORF1b	COVID-19	R L	View
39	33225958	E744D	RdRp	ORF1b	COVID-19	R L	View
40	33225958	G15327A	RdRp	ORF1b	COVID-19	R L	View
41	33225958	G15327C	RdRp	ORF1b	COVID-19	R L	View
42	33225958	G15327T	RdRp	ORF1b	COVID-19	R L	View
43	33225958	G15349C	RdRp	ORF1b	COVID-19	R L	View
44	33225958	G15359A	RdRp	ORF1b	COVID-19	R L	View
45	33225958	G15380T	RdRp	ORF1b	COVID-19	R L	View
46	33225958	G15384T	RdRp	ORF1b	COVID-19	R L	View
47	33225958	G15392A	RdRp	ORF1b	COVID-19	R L	View
48	33225958	G15406A	RdRp	ORF1b	COVID-19	R L	View
49	33225958	G15406T	RdRp	ORF1b	COVID-19	R L	View
50	33225958	G15412T	RdRp	ORF1b	COVID-19	R L	View
51	33225958	G15418T	RdRp	ORF1b	COVID-19	R L	View
52	33225958	G15438T	RdRp	ORF1b	COVID-19	R L	View
53	33225958	G15439A	RdRp	ORF1b	COVID-19	R L	View
54	33225958	G15444T	RdRp	ORF1b	COVID-19	R L	View
55	33225958	G15448A	RdRp	ORF1b	COVID-19	R L	View
56	33225958	G15448T	RdRp	ORF1b	COVID-19	R L	View
57	33225958	G15451A	RdRp	ORF1b	COVID-19	R L	View
58	33225958	G15452T	RdRp	ORF1b	COVID-19	R L	View
59	33225958	G15463T	RdRp	ORF1b	COVID-19	R L	View
60	33225958	G15472T	RdRp	ORF1b	COVID-19	R L	View
61	33225958	G15488T	RdRp	ORF1b	COVID-19	R L	View
62	33225958	G15535T	RdRp	ORF1b	COVID-19	R L	View
63	33225958	G15538A	RdRp	ORF1b	COVID-19	R L	View
64	33225958	G15571T	RdRp	ORF1b	COVID-19	R L	View
65	33225958	G15574A	RdRp	ORF1b	COVID-19	R L	View
66	33225958	G15575T	RdRp	ORF1b	COVID-19	R L	View
67	33225958	G15586T	RdRp	ORF1b	COVID-19	R L	View
68	33225958	G15589T	RdRp	ORF1b	COVID-19	R L	View
69	33225958	G15594T	RdRp	ORF1b	COVID-19	R L	View
70	33225958	G15598T	RdRp	ORF1b	COVID-19	R L	View
71	33225958	G15602A	RdRp	ORF1b	COVID-19	R L	View
72	33225958	G15627T	RdRp	ORF1b	COVID-19	R L	View
73	33225958	G15638A	RdRp	ORF1b	COVID-19	R L	View
74	33225958	G15652T	RdRp	ORF1b	COVID-19	R L	View
75	33225958	G15664A	RdRp	ORF1b	COVID-19	R L	View
76	33225958	G15672T	RdRp	ORF1b	COVID-19	R L	View
77	33225958	G15689A	RdRp	ORF1b	COVID-19	R L	View
78	33225958	G670C	RdRp	ORF1b	COVID-19	R L	View
79	33225958	G670S	RdRp	ORF1b	COVID-19	R L	View
80	33225958	G671S	RdRp	ORF1b	COVID-19	R L	View
81	33225958	G671V	RdRp	ORF1b	COVID-19	R L	View
82	33225958	G678C	RdRp	ORF1b	COVID-19	R L	View
83	33225958	G683V	RdRp	ORF1b	COVID-19	R L	View
84	33225958	G712S	RdRp	ORF1b	COVID-19	R L	View
85	33225958	G712V	RdRp	ORF1b	COVID-19	R L	View
86	33225958	H642N	RdRp	ORF1b	COVID-19	R L	View
87	33225958	H725Y	RdRp	ORF1b	COVID-19	R L	View
88	33225958	H752Q	RdRp	ORF1b	COVID-19	R L	View
89	33225958	K718N	RdRp	ORF1b	COVID-19	R L	View
90	33225958	K718R	RdRp	ORF1b	COVID-19	R L	View
91	33225958	L630F	RdRp	ORF1b	COVID-19	R L	View
92	33225958	L636F	RdRp	ORF1b	COVID-19	R L	View
93	33225958	L636I	RdRp	ORF1b	COVID-19	R L	View
94	33225958	L638F	RdRp	ORF1b	COVID-19	R L	View
95	33225958	L648F	RdRp	ORF1b	COVID-19	R L	View
96	33225958	L727F	RdRp	ORF1b	COVID-19	R L	View
97	33225958	L749M	RdRp	ORF1b	COVID-19	R L	View
98	33225958	M629I	RdRp	ORF1b	COVID-19	R L	View
99	33225958	M633T	RdRp	ORF1b	COVID-19	R L	View
100	33225958	M666I	RdRp	ORF1b	COVID-19	R L	View
101	33225958	M668I	RdRp	ORF1b	COVID-19	R L	View
102	33225958	N705D	RdRp	ORF1b	COVID-19	R L	View
103	33225958	N734T	RdRp	ORF1b	COVID-19	R L	View
104	33225958	N734Y	RdRp	ORF1b	COVID-19	R L	View
105	33225958	N743S	RdRp	ORF1b	COVID-19	R L	View
106	33225958	P627S	RdRp	ORF1b	COVID-19	R L	View
107	33225958	R640H	RdRp	ORF1b	COVID-19	R L	View
108	33225958	R640S	RdRp	ORF1b	COVID-19	R L	View
109	33225958	R651H	RdRp	ORF1b	COVID-19	R L	View
110	33225958	R721H	RdRp	ORF1b	COVID-19	R L	View
111	33225958	R733K	RdRp	ORF1b	COVID-19	R L	View
112	33225958	R750C	RdRp	ORF1b	COVID-19	R L	View
113	33225958	R750H	RdRp	ORF1b	COVID-19	R L	View
114	33225958	S647I	RdRp	ORF1b	COVID-19	R L	View
115	33225958	T15338C	RdRp	ORF1b	COVID-19	R L	View
116	33225958	T15460C	RdRp	ORF1b	COVID-19	R L	View
117	33225958	T15539C	RdRp	ORF1b	COVID-19	R L	View
118	33225958	T15636A	RdRp	ORF1b	COVID-19	R L	View
119	33225958	T15665C	RdRp	ORF1b	COVID-19	R L	View
120	33225958	T15665G	RdRp	ORF1b	COVID-19	R L	View
121	33225958	T15682A	RdRp	ORF1b	COVID-19	R L	View
122	33225958	T15685A	RdRp	ORF1b	COVID-19	R L	View
123	33225958	T15696G	RdRp	ORF1b	COVID-19	R L	View
124	33225958	T643I	RdRp	ORF1b	COVID-19	R L	View
125	33225958	T644M	RdRp	ORF1b	COVID-19	R L	View
126	33225958	T739I	RdRp	ORF1b	COVID-19	R L	View
127	33225958	V637L	RdRp	ORF1b	COVID-19	R L	View
128	33225958	V667I	RdRp	ORF1b	COVID-19	R L	View
129	33225958	V675F	RdRp	ORF1b	COVID-19	R L	View
130	33225958	V700A	RdRp	ORF1b	COVID-19	R L	View
131	33225958	V700I	RdRp	ORF1b	COVID-19	R L	View
132	33225958	V720F	RdRp	ORF1b	COVID-19	R L	View
133	33225958	V742A	RdRp	ORF1b	COVID-19	R L	View
134	33225958	V742G	RdRp	ORF1b	COVID-19	R L	View
135	33225958	V742M	RdRp	ORF1b	COVID-19	R L	View
136	33225958	Y674H	RdRp	ORF1b	COVID-19	R L	View
137	33225958	Y719C	RdRp	ORF1b	COVID-19	R L	View
138	33225958	Y748F	RdRp	ORF1b	COVID-19	R L	View
139	33225958	Y748N	RdRp	ORF1b	COVID-19	R L	View