All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-33357233
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 33357233 D614G
S
S
COVID-19
R
View
2 33357233 D936H
S
S
COVID-19
R
View
3 33357233 D936Y
S
S
COVID-19
R
View
4 33357233 L5F
S
S
COVID-19
R
View
5 33357233 V3G
S
S
COVID-19
R
View
6 33357233 P323L
RdRp
ORF1b
COVID-19
R
View
7 33357233 V483G
RBD
S
COVID-19
R
View
8 33357233 S25L
NSP7
ORF1a
COVID-19
R
View
9 33357233 T1198I
NSP3
ORF1a
COVID-19
R
View
10 33357233 T1198K
NSP3
ORF1a
COVID-19
R
View
11 33357233 T1198R
NSP3
ORF1a
COVID-19
R
View
12 33357233 P91S
NSP2
ORF1a
COVID-19
R
View
13 33357233 T85I
NSP2
ORF1a
COVID-19
R
View
14 33357233 V198I
NSP2
ORF1a
COVID-19
R
View
15 33357233 P504L
NSP13
ORF1b
COVID-19
R
View
16 33357233 S539A
NSP13
ORF1b
COVID-19
R
View
17 33357233 S539Y
NSP13
ORF1b
COVID-19
R
View
18 33357233 V49I
NSP13
ORF1b
COVID-19
R
View
19 33357233 Y541A
NSP13
ORF1b
COVID-19
R
View
20 33357233 Y541C
NSP13
ORF1b
COVID-19
R
View
21 33357233 A208V
N
N
COVID-19
R
View
22 33357233 D103Y
N
N
COVID-19
R
View
23 33357233 G204R
N
N
COVID-19
R
View
24 33357233 R195K
N
N
COVID-19
R
View
25 33357233 R203K
N
N
COVID-19
R
View
26 33357233 R209T
N
N
COVID-19
R
View
27 33357233 S180I
N
N
COVID-19
R
View
28 33357233 S183Y
N
N
COVID-19
R
View
29 33357233 S188L
N
N
COVID-19
R
View
30 33357233 S190N
N
N
COVID-19
R
View
31 33357233 S193I
N
N
COVID-19
R
View
32 33357233 S194L
N
N
COVID-19
R
View
33 33357233 S197L
N
N
COVID-19
R
View
34 33357233 S202N
N
N
COVID-19
R
View
35 33357233 T205I
N
N
COVID-19
R
View
36 33357233 Q57H
ORF3a
ORF3a
COVID-19
R
View
37 33357233 V483D COVID-19
R
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.