All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-33384909
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 33384909 D614G
S
S
COVID-19
R
View
2 33384909 L8V
S
S
COVID-19
R
View
3 33384909 A262S
S
S
COVID-19
R
View
4 33384909 G261D
S
S
COVID-19
R
View
5 33384909 N969S
S
S
COVID-19
R
View
6 33384909 Q498H
S
S
COVID-19
R
View
7 33384909 Y453F
S
S
COVID-19
R
View
8 33384909 F486L
RBM
S
COVID-19
R
View
9 33384909 L452M
RBM
S
COVID-19
R
View
10 33384909 N501T
RBM
S
COVID-19
R
View
11 33384909 K23S
ORF6
ORF6
COVID-19
R
View
12 33384909 R20S
ORF6
ORF6
COVID-19
R
View
13 33384909 G224C
ORF3a
ORF3a
COVID-19
R
View
14 33384909 H182L
ORF3a
ORF3a
COVID-19
R
View
15 33384909 H182Y
ORF3a
ORF3a
COVID-19
R
View
16 33384909 L219V
ORF3a
ORF3a
COVID-19
R
View
17 33384909 T229I
ORF3a
ORF3a
COVID-19
R
View
18 33384909 G4177E
NSP9
ORF1a
COVID-19
R
View
19 33384909 I3512T
NSP5
ORF1a
COVID-19
R
View
20 33384909 I3522V
NSP5
ORF1a
COVID-19
R
View
21 33384909 D2101G
NSP3
ORF1a
COVID-19
R
View
22 33384909 D953Y
NSP3
ORF1a
COVID-19
R
View
23 33384909 H1113Y
NSP3
ORF1a
COVID-19
R
View
24 33384909 I1508V
NSP3
ORF1a
COVID-19
R
View
25 33384909 K1202N
NSP3
ORF1a
COVID-19
R
View
26 33384909 M1588K
NSP3
ORF1a
COVID-19
R
View
27 33384909 P1096L
NSP3
ORF1a
COVID-19
R
View
28 33384909 V1052I
NSP3
ORF1a
COVID-19
R
View
29 33384909 A372V
NSP2
ORF1a
COVID-19
R
View
30 33384909 A405T
NSP2
ORF1a
COVID-19
R
View
31 33384909 E352Q
NSP2
ORF1a
COVID-19
R
View
32 33384909 E743V
NSP2
ORF1a
COVID-19
R
View
33 33384909 H388Y
NSP2
ORF1a
COVID-19
R
View
34 33384909 R398C
NSP2
ORF1a
COVID-19
R
View
35 33384909 A6544T
NSP15
ORF1b
COVID-19
R
View
36 33384909 A5770D
NSP13
ORF1b
COVID-19
R
View
37 33384909 I5582V
NSP13
ORF1b
COVID-19
R
View
38 33384909 M4588I
NSP12
ORF1b
COVID-19
R
View
39 33384909 T4418I
NSP12
ORF1b
COVID-19
R
View
40 33384909 T5195I
NSP12
ORF1b
COVID-19
R
View
41 33384909 K4377E
NSP10
ORF1a
COVID-19
R
View
42 33384909 P199Q
N
N
COVID-19
R
View
43 33384909 P80L
N
N
COVID-19
R
View
44 33384909 R41L
N
N
COVID-19
R
View
45 33384909 T247I
N
N
COVID-19
R
View
46 33384909 T175M
M
M
COVID-19
R
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.