All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-33920487
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 33920487 A222V
S
S
COVID-19
G
R
View
2 33920487 A220V
N
N
COVID-19
G
R
View
3 33920487 Q57H
ORF3a
ORF3a
COVID-19
G
R
View
4 33920487 T85I
NSP2
ORF1a
COVID-19
G
R
View
5 33920487 D614G
S
S
COVID-19
G
R
View
6 33920487 P323L
RdRp
ORF1b
COVID-19
G
R
View
7 33920487 L18F
S
S
COVID-19
R
View
8 33920487 N439K
S
S
COVID-19
R
View
9 33920487 S477N
S
S
COVID-19
R
View
10 33920487 G172V
ORF3a
ORF3a
COVID-19
R
View
11 33920487 P67S
N
N
COVID-19
R
View
12 33920487 S194L
N
N
COVID-19
R
View
13 33920487 P199L
N
N
COVID-19
R
View
14 33920487 R203K
N
N
COVID-19
R
View
15 33920487 G204R
N
N
COVID-19
R
View
16 33920487 M234I
N
N
COVID-19
R
View
17 33920487 A376T
N
N
COVID-19
R
View
18 33920487 I120F
NSP2
ORF1a
COVID-19
R
View
19 33920487 K218R
NSP13
ORF1b
COVID-19
R
View
20 33920487 E261D
NSP13
ORF1b
COVID-19
R
View
21 33920487 H290Y
NSP13
ORF1b
COVID-19
R
View
22 33920487 A185S
NSP12
ORF1b
COVID-19
R
View
23 33920487 V776L
NSP12
ORF1b
COVID-19
R
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.