All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-34578363
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 34578363 A222V
S
S
COVID-19
R
L
View
2 34578363 K77T
S
S
COVID-19
R
L
View
3 34578363 L116F
ORF7a
ORF7a
COVID-19
R
L
View
4 34578363 A1306S
ORF1ab
ORF1ab
COVID-19
R
L
View
5 34578363 A3209V
ORF1ab
ORF1ab
COVID-19
R
L
View
6 34578363 A6319V
ORF1ab
ORF1ab
COVID-19
R
L
View
7 34578363 D2980N
ORF1ab
ORF1ab
COVID-19
R
L
View
8 34578363 F3138S
ORF1ab
ORF1ab
COVID-19
R
L
View
9 34578363 G5063S
ORF1ab
ORF1ab
COVID-19
R
L
View
10 34578363 P2046L
ORF1ab
ORF1ab
COVID-19
R
L
View
11 34578363 P2287S
ORF1ab
ORF1ab
COVID-19
R
L
View
12 34578363 P309L
ORF1ab
ORF1ab
COVID-19
R
L
View
13 34578363 P5401L
ORF1ab
ORF1ab
COVID-19
R
L
View
14 34578363 T3255I
ORF1ab
ORF1ab
COVID-19
R
L
View
15 34578363 T3446A
ORF1ab
ORF1ab
COVID-19
R
L
View
16 34578363 T3750I
ORF1ab
ORF1ab
COVID-19
R
L
View
17 34578363 V2930L
ORF1ab
ORF1ab
COVID-19
R
L
View
18 34578363 V3718A
ORF1ab
ORF1ab
COVID-19
R
L
View
19 34578363 G215C
N
N
COVID-19
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.