All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-35778549
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35778549 D484E
S
S
COVID-19
G
S
L
View
2 35778549 H655Y
S
S
COVID-19
G
S
L
View
3 35778549 N63T
S
S
COVID-19
G
S
L
View
4 35778549 R682Q
S
S
COVID-19
G
S
L
View
5 35778549 T63N
S
S
COVID-19
G
S
L
View
6 35778549 V62G
S
S
COVID-19
G
S
L
View
7 35778549 Y655H
S
S
COVID-19
G
S
L
View
8 35778549 V62L
ORF8
ORF8
COVID-19
G
S
L
View
9 35778549 A1156D
ORF1ab
ORF1ab
COVID-19
G
S
L
View
10 35778549 A427S
ORF1ab
ORF1ab
COVID-19
G
S
L
View
11 35778549 D1157E
ORF1ab
ORF1ab
COVID-19
G
S
L
View
12 35778549 F1154L
ORF1ab
ORF1ab
COVID-19
G
S
L
View
13 35778549 F438V
ORF1ab
ORF1ab
COVID-19
G
S
L
View
14 35778549 I1091K
ORF1ab
ORF1ab
COVID-19
G
S
L
View
15 35778549 I1159L
ORF1ab
ORF1ab
COVID-19
G
S
L
View
16 35778549 K1902Q
ORF1ab
ORF1ab
COVID-19
G
S
L
View
17 35778549 N1898K
ORF1ab
ORF1ab
COVID-19
G
S
L
View
18 35778549 P361A
ORF1ab
ORF1ab
COVID-19
G
S
L
View
19 35778549 R1163S
ORF1ab
ORF1ab
COVID-19
G
S
L
View
20 35778549 R437G
ORF1ab
ORF1ab
COVID-19
G
S
L
View
21 35778549 S1161A
ORF1ab
ORF1ab
COVID-19
G
S
L
View
22 35778549 S2695T
ORF1ab
ORF1ab
COVID-19
G
S
L
View
23 35778549 T1168S
ORF1ab
ORF1ab
COVID-19
G
S
L
View
24 35778549 Y1899S
ORF1ab
ORF1ab
COVID-19
G
S
L
View
25 35778549 Y1900D
ORF1ab
ORF1ab
COVID-19
G
S
L
View
26 35778549 F66Y
N
N
COVID-19
G
S
L
View
27 35778549 P67H
N
N
COVID-19
G
S
L
View
28 35778549 D614G COVID-19
G
S
L
View
29 35778549 E484D COVID-19
G
S
L
View
30 35778549 E96D COVID-19
G
S
L
View
31 35778549 N148K COVID-19
G
S
L
View
32 35778549 N74K COVID-19
G
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.